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Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms

Cancer • • ObesityDec 14 07

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have associated obesity with a range of cancer types, although the mechanisms by which obesity induces or promotes tumorigenesis vary by cancer site.

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Obesity and cancer: the risks, science, and potential management strategies

Cancer • • ObesityDec 14 07

Overweight and obesity increase the risk of developing several cancers. Once cancer develops, individuals may be at increased risk of recurrence and poorer survival if they are overweight or obese. A statistically significant association between overweight or obesity and breast cancer recurrence or survival has been observed in the majority of population-based case series; however, adiposity has been shown to have less of an effect on prognosis in the clinical trial setting.

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Dementia raises death risk in oldest elderly

NeurologyDec 14 07

Alzheimer’s disease and other forms of dementia may have a particularly strong impact on life expectancy among the oldest elderly.

In a study published in the journal Neurology, researchers found that 95-year-olds with dementia were less likely to survive to their 100th birthday than those without dementia. 

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Exercise more to live longer: study

Public HealthDec 14 07

Following national recommendations for physical activity can lengthen your life, results of a study indicate.

In the study, people 50 to 71 years old who got at least 30 minutes of moderate physical activity at least five days a week—as recommended in U.S. national guidelines—were 27 percent less likely to die over the next six or seven years, Dr. Michael F. Leitzmann of the National Cancer Institute in Bethesda, Maryland and colleagues found. 

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Ingredient in human semen may enhance HIV infection

AIDS/HIVDec 14 07

An ingredient in human semen may actually help the HIV virus infect cells, German researchers said on Thursday.

They said naturally occurring prostatic acidic phosphatase or PAP, an enzyme produced by the prostate, can form tiny fibers called amyloid fibrils that can capture bits of the human immunodeficiency virus and usher it into cells.

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Workplace opportunities and stresses are both increasing

Public Health • • StressDec 14 07

Teamworking and other modern employment practices can put as much strain on a woman’s family relationships as working an extra 120 hours a year, an extensive study of the British workforce funded by the Economic and Social Research Council suggests.

The research finds that while British employers have maintained long-term career relationships with employees in spite of competitive market pressures, they have devised ways of extracting more effort and higher performance. These practices include team-based forms of work organization, individual performance-related pay, and policies that emphasize the development of individual potential. 

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