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An ectopic pregnancy occurs when a fertilized egg implants outside of the uterus. The most common site is within a fallopian tube. More rarely an embryo may implant within an ovary, in the cervix, or on the abdominal wall


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Sleep Duration May Play Important Role in Childhood Obesity

Obesity • • Sleep AidFeb 07 08

Less sleep can increase a child’s risk of being overweight or obese, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health. Their analysis of epidemiological studies found that with each additional hour of sleep, the risk of a child being overweight or obese dropped by 9 percent. The results are published in the February 2008 edition Obesity, the journal of The Obesity Society.

“Our analysis of the data shows a clear association between sleep duration and the risk for overweight or obesity in children. The risk declined with more sleep,” said Youfa Wang, MD, PhD, senior author of the study and associate professor with the Bloomberg School’s Center for Human Nutrition. “Desirable sleep behavior may be an important low cost means for preventing childhood obesity and should be considered in future intervention studies. Our findings may also have important implications in societies where children do not have adequate sleep due to the pressure for academic excellence and where the prevalence of obesity is rising, such as in many East Asian countries.”

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Close ties between parents and babies yield benefits for preschoolers

Psychiatry / PsychologyFeb 07 08

Having close ties with parents is obviously good for preschoolers, but what does that really mean? It means that the preschoolers are better able to control their own behavior by showing patience, deliberation, restraint, and even maturity.

That’s the finding of a new study conducted by researchers at the University of Iowa and published in the January/February 2008 issue of the journal Child Development.

The researchers looked at 102 mostly white families—mothers, fathers, and babies—who had volunteered for the study from the time the children were 7 months old until they were almost 4 and a half years old. Repeated observations were carried out in the families’ homes and in a laboratory. In the first two years, the researchers observed how parents and children related to each other, particularly whether they were in sync, picked up on each other’s cues, communicated well, and enjoyed each other’s company. In short, they gauged whether the parents and children had developed a close, positive, reciprocal, cooperative, and mutually responsive relationship.

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NIH scientists detect fatal copper disorder at birth

Brain • • NeurologyFeb 07 08

A test developed by NIH scientists could greatly extend the survival of infants with Menkes disease, a rare, otherwise fatal disorder of copper metabolism. The test allows for early diagnosis of the condition, when the chance for successful treatment is greatest. Their work is described in the February 7 New England Journal of Medicine.

Untreated, Menkes disease results in irreparable harm to the brain and nervous system. Treatment consists of injections with a copper-containing drug. Children with Menkes disease typically die during the first decade of life. Previously, there was no blood test for early detection of Menkes disease.

“The study represents an important advance in the diagnosis and treatment of a rare but devastating genetic disorder,” said Duane Alexander, M.D., Director of NIH’s National Institute of Child Health and Human Development (NICHD), the lead NIH institute that conducted the study. “The laboratory techniques the researchers used to detect Menkes disease eventually may provide the basis for a newborn screening test to identify children with Menkes at birth, so they have the greatest chance to benefit from treatment.”

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High Blood Pressure Pill Cuts Risk of Parkinson’s Disease

Heart • • NeurologyFeb 07 08

People taking a widely used group of drugs known as calcium channel blockers to treat high blood pressure also appear to be cutting their risk of Parkinson’s disease, according to a study published in the February 6, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.

The study involved 7,374 men and women over age 40. Half of the group had Parkinson’s disease; the other half did not have Parkinson’s disease. Among both groups, nearly half used high blood pressure medications, such as calcium channel blockers, ACE inhibitors, AT II antagonists and beta blockers.

The study found people who were currently long-term users of calcium channel blockers to treat high blood pressure lowered their risk of Parkinson’s disease by 23 percent compared to people who didn’t take the drugs. There was no such effect among people taking ACE inhibitors, AT II antagonists and beta blockers.

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