High doses of vitamin D safe for children
Giving school children very high doses of vitamin D is safe, and may be necessary to bring their blood levels of the nutrient up to the amount necessary for optimum bone growth and health, a new study shows.
Insufficiency in vitamin D is common in children around the world, but there is little data on how much supplementation kids need, or even how much vitamin D they should have in their blood, Dr. Ghada E.-Hajj Fuleihan of the American University of Beirut in Lebanon told Reuters Health. “In the pediatric literature, we don’t have a lot to guide us,” she said.
In a previous study, Fuleihan and colleagues found that giving 10- to 17-year-olds relatively high doses of vitamin D3 increased their bone mass and bone area, as well as lean mass. In the current study, they report on both the short- and long-term safety of high-dose supplementation.
Depression common among Rwandan youth who head households
More than half of orphaned youth age 12 to 24 who head households in rural Rwanda meet criteria for depression, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
The combined effects of the 1994 genocide and the HIV epidemic give Rwanda one of the highest numbers of orphans in the world—an estimated 290,000 in 2005, according to background information in the article. “Most African orphans have been absorbed into informal fostering systems,” the authors write. “Such systems, however, are increasingly overwhelmed, and many orphans either head households or live on the street.”
Neil W. Boris, M.D., of the Tulane University School of Medicine, New Orleans, and colleagues assessed depressive symptoms in 539 youth in Rwanda who served as heads of households. Trained interviewers met with the youth (age 24 or younger, average age 20) and administered scales measuring symptoms of grief, depression, adult support and marginalization from the community. Questions about demographics, health, vulnerability and risky behaviors also were included.
The first autism disease genes
The autistic disorder was first described, more than sixty years ago, by Dr. Leo Kanner of the Johns Hopkins Hospital (USA), who created the new label ´early infantile autism´. At the same time an Austrian scientist, Dr. Hans Asperger, described a milder form of the disorder that became known as Asperger Syndrome, characterised by higher cognitive abilities and more normal language function. Today, both disorders are classified in the continuum of ´Pervasive Developmental Disorders´ (PDD), more often referred to as Autism Spectrum Disorders (ASD).
The prevalence of (classic) autism in the general population is about 15-20 in 10.000, while all Autism Spectrum Disorders (ASD) affect about 60 in 10.000 children. Males are affected four times more often than females. In approximately 10% of cases, autism is associated with a recognized cause, such as Fragile X Syndrome, Tuberous Sclerosis or diverse chromosomal abnormalities (mean observed rates between 5-10%), but in a vast majority of cases, no known causes are associated with autism.
Family therapy helps relieve depression symptoms in bipolar teens
Family-focused therapy, when combined with medication, appears effective in stabilizing symptoms of depression among teens with bipolar disorder, according to a report in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Between one-half and two-thirds of patients with bipolar disorder develop the condition before age 18, according to background information in the article. “Early onset of illness is associated with an unremitting course of illness, frequent switches of polarity, mixed episodes, psychosis, a high risk of suicide and poor functioning or quality of life,” the authors write. “The past decade has witnessed a remarkable increase in diagnoses of bipolar disorder in children and adolescents and, correspondingly, drug trials for patients with early-onset disorder. There has been comparatively little controlled examination of psychotherapy for pediatric patients.”
