3-rx.comCustomer Support
HomeAbout UsFAQContactHelp
News Center
Health Centers
Medical Encyclopedia
Drugs & Medications
Diseases & Conditions
Medical Symptoms
Med. Tests & Exams
Surgery & Procedures
Injuries & Wounds
Diet & Nutrition
Special Topics

\"$alt_text\"');"); } else { echo"\"$alt_text\""; } ?>

Join our Mailing List


You are here : 3-RX.com > Home > Asthma -

Study links weight loss to benefits for asthma sufferers

AsthmaAug 19, 05

Dr. Christie Ballantyne, lead investigator of a study linking Obesity and Asthma, says patients who lost weight saw decreased levels of eotaxin—an inflammatory mediator known to play a key role in Asthma flare-ups—meaning weight loss may be a very effective therapy for treating asthma sufferers. If you enjoy this article, you may also be interested in an article entitled ‘Asthma explained by common allergy to milk and dairy products.’


  • Research presented at the American Diabetes Association’s Scientific Sessions today showed that therapies targeting abdominal fat tissue, such as weight loss, may provide a new approach to treat Asthma.

  • “The incidence of asthma and Obesity is increasing worldwide, and asthma is often more severe in the obese,” said Dr. Christie Ballantyne, lead investigator of the study and director of the Center for Cardiovascular Disease Prevention at the Methodist DeBakey Heart Center in Houston.

  • “We found that fat tissue inside of the abdomen is an important source of eotaxin, which is an inflammatory mediator that is known to play a key role in asthma.”

  • According to research conducted by Dr. Ballantyne, obese patients’ eotaxin levels were significantly reduced with weight loss.

  • This finding is important because it may provide physicians and patients with a new approach to treat this debilitating disorder.

  • Circulating eotaxin levels were compared in obese vs. lean mice, obese humans vs. lean humans, and obese humans before and after weight loss.

  • Eotaxin mRNA levels were compared in fat tissue from obese vs. lean mice and in subcutaneous vs. visceral fat tissue from patients undergoing bariatric surgery.

  • Eotaxin levels were significantly higher in obese mice than lean mice, and mRNA levels in the fat tissue were positively correlated with serum levels of eotaxin.

  • Circulating eotaxin levels are increased in diet-induced Obesity in both mice and humans, and eotaxin mRNA levels were high in visceral adipose tissue in both species.

  • Diet-induced weight loss in humans led to a reduction in plasma eotaxin levels, demonstrating that clinical interventions that target Obesity can modulate systemic eotaxin levels.

  • This shows that eotaxin and other inflammatory mediators may link Obesity to Asthma, and targeting adiposity/eotaxin may have benefit in obese asthmatics.

    Print Version
    comments powered by Disqus

      Poorly controlled asthma costly
      Protein associated with allergic response causes airway changes in asthma patients
      Landmark Study Shows Suboptimal Asthma Care
      Acetaminophen use in adolescents linked to doubled risk of asthma
      Asthma and Eczema Sufferers Have a Lower Risk of Developing a Cancer
      ‘TIMely’ intervention for asthma
      Eliminating the source of asthma-causing immune molecules
      Does breastfeeding protect against asthma?
      Sleep apnea as common as asthma in German kids
      Parent mentors can improve the asthmatic care of minority children, UT Southwestern researchers find
      Sweet! Sugared Polymer a New Weapon Against Allergies and Asthma
      Asthma: Epidemiology, etiology and risk factors


    Home | About Us | FAQ | Contact | Advertising Policy | Privacy Policy | Bookmark Site