Amiodarone (Systemic)

Brand Names : Cordarone, Cordarone I.V., Cordarone Intravenous, pms-Amiodarone

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For amiodarone, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to amiodarone. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Amiodarone has been shown to cause thyroid problems in babies whose mothers took amiodarone when pregnant. In addition, there is concern that amiodarone could cause slow heartbeat in the newborn. However, this medicine may be needed in serious situations that threaten the mother's life. Be sure you have discussed this with your doctor before taking this medicine.

Breast-feeding - Although amiodarone passes into breast milk, it has not been shown to cause problems in nursing babies. However, amiodarone has been shown to cause growth problems in rats. It may be necessary for you to stop breast-feeding during treatment. Be sure you have discussed the risks and benefits of the medicine with your doctor.

Children - Amiodarone can cause serious side effects in any patient. Therefore, it is especially important that you discuss with the child's doctor the good that this medicine may do as well as the risks of using it.

Older adults - Elderly patients may be more likely to get thyroid problems with this medicine. Also, difficulty in walking and numbness, tingling, trembling, or weakness in hands or feet are more likely to occur in the elderly.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking amiodarone, it is especially important that your health care professional know if you are taking any of the following:

• Anticoagulants (blood thinners) or
• Other heart medicine or
• Phenytoin (e.g., Dilantin) - Effects may be increased

Other medical problems - The presence of other medical problems may affect the use of amiodarone. Make sure you tell your doctor if you have any other medical problems, especially:

• Hepatitis, acute - Risk of adverse effects is increased.
• Liver disease - Effects of amiodarone may be increased because of slower removal from the body

• Thyroid problems - Risk of overactive or underactive thyroid is increased