Antifibrinolytic Agents (Systemic)

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For antifibrinolytic agents, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to aminocaproic acid or tranexamic acid. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Studies on birth defects have not been done in humans. However, these medicines have been given to pregnant women without causing birth defects or other problems.

Studies on effects of aminocaproic acid in pregnancy have not been done in animals. Tranexamic acid has not been shown to cause birth defects or other problems in animal studies.

Breast-feeding - These medicines have not been reported to cause problems in nursing babies. However, small amounts of tranexamic acid pass into the breast milk.

Children - Although there is no specific information comparing use of aminocaproic acid or tranexamic acid in children with use in other age groups, these medicines are not expected to cause different side effects or problems in children than they do in adults.

Older adults -

• For aminocaproic acid : Although there is no specific information comparing use of aminocaproic acid in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.
• For tranexamic acid : Tranexamic acid has been tested and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your health care professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems - The presence of other medical problems may affect the use of antifibrinolytic agents. Make sure you tell your doctor if you have any other medical problems, especially:

• Blood clots or a history of medical problems caused by blood clots or
• Blood in the urine or
• Color vision problems or
• Heart disease or
• Kidney disease or
• Liver disease - The chance of side effects may be increased