Antifibrinolytic Agents (Systemic)
Proper Use of This MedicineTake this medicine only as directed by your doctor
. Do not take more
or less of it, do not take it more often, and do not take it for a longer
time than your doctor ordered. To do so may increase the chance of unwanted
effects.
Dosing - The dose of these medicines will be different
for different patients. Follow your doctor's orders or
the directions on the label
. The following information includes only
the average doses of these medicines. If your dose is
different, do not change it
unless your doctor tells you to do so.
For aminocaproic acid
-
To prevent or treat serious bleeding:
-
For oral
dosage forms (syrup or tablets):
-
Adults - For the first hour, the dose is 5 grams. Then the dose
is 1 or 1.25 grams per hour for eight hours.
-
Children - Dose is based on body weight or size and must be determined
by your doctor. For the first hour, the dose is usually 100 milligrams (mg)
per kilogram (kg) (45.4 mg per pound) of body weight. Then the dose is 33.3
mg per kg (15.1 mg per pound) of body weight per hour.
-
For injection
dosage form:
-
Adults - At first, the dose is 4 to 5 grams injected into a vein,
over a period of one hour. Then the dose is 1 gram per hour, injected into
a vein over a period of eight hours.
-
Children - Dose is based on body weight or size and must be determined
by your doctor. At first, the dose is usually 100 mg per kg (45.4 mg per pound)
of body weight, injected into a vein over a period of one hour. Then the dose
is 33.3 mg per kg (15.1 mg per pound) of body weight per hour, injected into
a vein.
For tranexamic acid
-
To prevent or treat serious bleeding after dental surgery:
-
For oral
dosage form (tablets):
-
Adults and children - Dose is based on body weight and must be
determined by your doctor. The dose is usually 25 milligrams (mg) per kilogram
(kg) (11.4 mg per pound) of body weight every six to eight hours, beginning
one day before surgery. After surgery, the dose is usually 25 mg per kg (11.4
mg per pound) of body weight every six to eight hours for two to eight days.
-
For injection
dosage form:
-
Adults and children - Dose is based on body weight and must be
determined by your doctor. The dose is usually 10 mg per kg (4.5 mg per pound)
of body weight, injected into a vein just before surgery. After surgery, the
dose is usually 10 mg per kg (4.5 mg per pound) of body weight, injected into
a vein every six to eight hours for seven to ten days.
Missed dose -
-
For aminocaproic acid
(e.g., Amicar):
If you miss a dose, take it as soon as possible. However, if you do not remember
until it is almost time for your next dose, double the next dose. Then go
back to your regular dosing schedule.
-
For tranexamic acid
(e.g., Cyklokapron):
If you miss a dose, take it as soon as possible. Then take any remaining doses
for the day at regularly spaced times. Do not double doses. If you have any
questions about this, check with your doctor.
Storage - To store this medicine:
-
Keep out of the reach of children.
-
Store away from heat and direct light.
-
Do not store the tablet form of this medicine in the bathroom, near
the kitchen sink, or in other damp places. Heat or moisture may cause the
medicine to break down.
-
Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.
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