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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Antifibrinolytic Agents : Proper Use

Antifibrinolytic Agents (Systemic)

Antifibrinolytic Agents | Before Using | Proper Use | Precautions | Side Effects

Proper Use of This Medicine

Take this medicine only as directed by your doctor . Do not take more or less of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of unwanted effects.

Dosing - The dose of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

    For aminocaproic acid
  • To prevent or treat serious bleeding:
    • For oral dosage forms (syrup or tablets):
      • Adults - For the first hour, the dose is 5 grams. Then the dose is 1 or 1.25 grams per hour for eight hours.
      • Children - Dose is based on body weight or size and must be determined by your doctor. For the first hour, the dose is usually 100 milligrams (mg) per kilogram (kg) (45.4 mg per pound) of body weight. Then the dose is 33.3 mg per kg (15.1 mg per pound) of body weight per hour.
    • For injection dosage form:
      • Adults - At first, the dose is 4 to 5 grams injected into a vein, over a period of one hour. Then the dose is 1 gram per hour, injected into a vein over a period of eight hours.
      • Children - Dose is based on body weight or size and must be determined by your doctor. At first, the dose is usually 100 mg per kg (45.4 mg per pound) of body weight, injected into a vein over a period of one hour. Then the dose is 33.3 mg per kg (15.1 mg per pound) of body weight per hour, injected into a vein.
    For tranexamic acid
  • To prevent or treat serious bleeding after dental surgery:
    • For oral dosage form (tablets):
      • Adults and children - Dose is based on body weight and must be determined by your doctor. The dose is usually 25 milligrams (mg) per kilogram (kg) (11.4 mg per pound) of body weight every six to eight hours, beginning one day before surgery. After surgery, the dose is usually 25 mg per kg (11.4 mg per pound) of body weight every six to eight hours for two to eight days.
    • For injection dosage form:
      • Adults and children - Dose is based on body weight and must be determined by your doctor. The dose is usually 10 mg per kg (4.5 mg per pound) of body weight, injected into a vein just before surgery. After surgery, the dose is usually 10 mg per kg (4.5 mg per pound) of body weight, injected into a vein every six to eight hours for seven to ten days.

Missed dose -

  • For aminocaproic acid (e.g., Amicar): If you miss a dose, take it as soon as possible. However, if you do not remember until it is almost time for your next dose, double the next dose. Then go back to your regular dosing schedule.
  • For tranexamic acid (e.g., Cyklokapron): If you miss a dose, take it as soon as possible. Then take any remaining doses for the day at regularly spaced times. Do not double doses. If you have any questions about this, check with your doctor.

Storage - To store this medicine:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Do not store the tablet form of this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

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Antifibrinolytic Agents: Before Using

 

Antifibrinolytic Agents: Precautions



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