Antifungals, Azole (Vaginal)
Before Using This MedicineIn deciding to use a medicine,
the risks of using the medicine must be weighed against the good it will do.
This is a decision you and your doctor will make. For vaginal azoles, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to any of the azoles. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Studies have not been done in humans for use of all
azole antifungals during the first trimester of pregnancy. These medicines
are safe and effective when used for at least 7 days during the second and
third trimesters of pregnancy. However, check with your doctor before using
this medicine during the first trimester of pregnancy. Also, use of 1- and
3-day treatments may not be effective during pregnancy.
Breast-feeding - It is not known whether vaginal azoles pass into
the breast milk. However, these medicines have not been shown to cause problems
in nursing babies.
Children - Studies on these medicines have been done only in
adult patients, and there is no specific information comparing use of vaginal
azoles in children with use in other age groups. It is recommended that these
medicines not be used in children up to 12 years of age.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults. Although there is no specific information
comparing use of vaginal azoles in the elderly with use in other age groups,
they are not expected to cause different side effects or problems in older
people than they do in younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are using any other vaginal prescription or nonprescription
(over-the-counter [OTC]) medicine. When you are taking miconazole, it is especially
important that your health care professional know if you are taking any of
the following:
-
Warfarin (e.g., Coumadin; Warfilone) - Using with warfarin may
cause bleeding and/or bruising
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