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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Antihistamines, Decongestants, and Anticholinergics : Side Effects

Antihistamines, Decongestants, and Anticholinergics (Systemic)

Antihistamines, Decongestants, and Anticholinergics | Before Using | Proper Use | Precautions | Side Effects

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Get emergency help immediately if any of the following symptoms of overdose occur :

Clumsiness or unsteadiness; convulsions (seizures); drowsiness (severe); dryness of mouth, nose, or throat (severe); fast heartbeat; flushing or redness of face; hallucinations (seeing, hearing, or feeling things that are not there); headache (continuing); shortness of breath or troubled breathing; trouble in sleeping

For pseudoephedrine only

Unusual nervousness, restlessness, or excitement

Also, check with your doctor as soon as possible if any of the following side effects occur:


      Irregular or slow heartbeat; mood or mental changes; skin rash, hives, or itching; sore throat and fever; tightness in chest; unusual bleeding or bruising; unusual tiredness or weakness

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your health care professional if any of the following side effects continue or are bothersome:

    More common

      Drowsiness; nervousness; restlessness; thickening of mucus; trouble in sleeping

    Less common - more common with high doses

      Blurred vision; confusion; difficult or painful urination; dizziness; dryness of mouth, nose, or throat; fast or pounding heartbeat; headache; increased sweating; loss of appetite; nausea or vomiting; nightmares; ringing or buzzing in ears; trembling; unusual excitement, nervousness, restlessness, or irritability; unusual paleness; weakness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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Antihistamines, Decongestants, and Anticholinergics: Precautions


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