Benznidazole (Systemic)
Brand Names : Radanil, Rochagan, Ro7-1051
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For benznidazole, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to benznidazole. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Studies have not been done in pregnant women. The
World Health Organization (WHO) does not recommend the use of benznidazole
during the first 3 months of pregnancy. However, this medicine has not been
shown to cause birth defects or other problems in animal studies.
Breast-feeding - It is not known whether benznidazole passes into
breast milk. Although most medicines pass into breast milk in small amounts,
many of them may be used safely while breast-feeding. Mothers who are taking
this medicine and who wish to breast-feed should discuss this with their doctor.
Children - Although there is no specific information comparing
use of benznidazole in children with use in other age groups, this medicine
is not expected to cause different side effects or problems in children than
it does in adults.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing use
of benznidazole in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
benznidazole, it is especially important that your health care professional
know if you are taking any of the following:
-
Alcohol - Taking alcohol with benznidazole may cause unwanted
effects such as stomach cramps, nausea, vomiting, headache, or redness of
face
-
Inflammation or pain medicine, except narcotics, such as aspirin,
or
-
Anticoagulants (blood thinners), such as warfarin (e.g., Coumadin,
Panwarfarin, Warfilone) - Taking aspirin or anticoagulants with benznidazole
may increase the chance of bleeding
Other medical problems - The presence of other medical
problems may affect the use of benznidazole. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Blood disease or
-
Kidney disease or
-
Liver disease - Patients with these conditions may have an increased
chance of side effects
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