Chymopapain (Parenteral-Local)

Brand Names : Chymodiactin

Category

• Chemonucleolytic, herniated lumbar intervertebral disk therapy

Description

Chymopapain (KYE-moe-pa-pane) is injected directly into a herniated (``slipped'') disk in the spine to dissolve part of the disk and relieve the pain and other problems caused by the disk pressing on a nerve. Before you receive chymopapain, you will be given an anesthetic (either a general anesthetic to put you to sleep or a local anesthetic).

Very rarely, use of chymopapain may cause serious side effects, including paralysis of the legs or death. Another dangerous side effect of chymopapain injection is a severe allergic reaction called anaphylaxis. This side effect occurs in less than 1% of the patients receiving the medicine, but it occurs more often in women than in men. Before receiving chymopapain, you should discuss its use, and the possibility of anaphylaxis or other serious side effects, with your doctor.

Chymopapain injections are given only in a hospital, usually in an operating room, by your surgeon. This medicine is available in the following dosage form:

Parenteral
• Injection (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

• Chymodiactin

In Canada -

• Chymodiactin