Dantrolene (Systemic)

Brand Names : Dantrium, Dantrium Intravenous

Category

• Antispastic
• Duchenne muscular dystrophy therapy adjunct
• Malignant hyperthermia therapy adjunct
• Muscle phosphorylase deficiency therapy adjunct
• Neuroleptic malignant syndrome therapy adjunct

Description

Dantrolene (DAN-troe-leen) is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by certain medical problems such as multiple sclerosis (MS), cerebral palsy, stroke, or injury to the spine. Dantrolene does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition. Dantrolene acts directly on the muscles to produce its relaxant effects.

Dantrolene is also used to prevent or treat a medical problem called malignant hyperthermia that may occur in some people during or following surgery or anesthesia. Malignant hyperthermia consists of a group of symptoms including very high fever, fast and irregular heartbeat, and breathing problems. It is believed that the tendency to develop malignant hyperthermia is inherited.

Dantrolene has been shown to cause cancer and noncancerous tumors in some animals (but not in others) when given in large doses for a long time. It is not known whether long-term use of dantrolene causes cancer or tumors in humans. Before taking this medicine, be sure that you have discussed this with your doctor.

This medicine is available only with your doctor's prescription, in the following dosage forms:

Oral
• Capsules (U.S. and Canada)

Parenteral
• Injection (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

• Dantrium
• Dantrium Intravenous

In Canada -

• Dantrium
• Dantrium Intravenous