Diuretics, Potassium-sparing (Systemic)
Side Effects of This MedicineIn rats, spironolactone has been found to increase the risk of tumors.
It is not known if spironolactone increases the chance of tumors in humans.
Signs and symptoms of too much potassium
Confusion; irregular heartbeat; nervousness; numbness or tingling in
hands, feet, or lips; shortness of breath or difficult
breathing; unusual tiredness or weakness; weakness or heaviness of legs
Other side
effects may occur that usually do not need medical attention. These side effects
may go away during treatment as your body adjusts to the medicine. However,
check with your doctor if any of the following side effects continue or are
bothersome:
More common (less common with amiloride and triamterene)
Less common
For amiloride, spironolactone, and triamterene
For amiloride only (in addition to effects listed above)
For spironolactone only (in addition to effects listed above for spironolactone)
Breast tenderness in females; clumsiness; deepening of voice in females; enlargement of breasts in males; inability to have
or keep an erection; increased hair growth in females; irregular menstrual periods; sweating
For triamterene only (in addition to effects listed above for triamterene)
Signs and symptoms of too little sodium
For male patients
:
-
Spironolactone sometimes causes enlarged breasts in males, especially
when they take large doses of it for a long time. Breasts usually decrease
in size gradually over several months after this medicine is stopped. If you
have any questions about this, check with your doctor.
Other side effects not listed above may also occur in
some patients. If you notice any other effects, check with your doctor.
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