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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Fentanyl : Side Effects

Fentanyl (Transdermal-Systemic)

Brand Names : Duragesic

Fentanyl | Before Using | Proper Use | Precautions | Side Effects

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Get emergency help immediately if the following signs of overdose occur :

      Cold, clammy skin; convulsions (seizures); drowsiness that is so severe that you are not able to answer when spoken to or, if asleep, cannot be awakened; low blood pressure; pinpoint pupils of eyes; slow heartbeat; very slow (fewer than 8 breaths a minute) or troubled breathing

    Also, check with your doctor as soon as possible if any of the following side effects occur:

      More common

        Decrease in amount of urine or in the frequency of urination; hallucinations (seeing, hearing, or feeling things that are not there)

      Less common

        Chest pain; difficulty in speaking; fainting; irregular heartbeat; mood or mental changes; problems with walking; redness, swelling, itching, or bumps on the skin at place of application; spitting blood


        Any change in vision; bladder pain; difficulty in speaking; fever with or without chills; fluid-filled blisters on skin; frequent urge to urinate; noisy breathing, shortness of breath, tightness in chest, or wheezing; red, thickened, or scaly skin; swelling of abdomen or stomach area; swollen and/or painful glands; unusual bruising

Incidence not known

Bloating or swelling of face, hands, lower legs and/or feet; rapid weight gain; fast or pounding heartbeat or pulse

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

    More common

      Abdominal or stomach pain that was not present before treatment; confusion; constipation; diarrhea; dizziness, drowsiness, or lightheadedness; false sense of well-being; feeling anxious; headache; indigestion; loss of appetite; nausea or vomiting; nervousness; sweating; weakness

    Less common

      Bloated feeling or gas; feeling anxious and restless at the same time; feeling of crawling, tingling, or burning of the skin; memory loss; unusual dreams

Incidence not known

Weight loss

After you stop using this medicine, your body may need time to adjust. The length of time this takes depends on the amount of medicine you were using and how long you used it. During this period of time check with your doctor if you notice any of the following side effects:

Anxiety; body aches; diarrhea; fast heartbeat; fever, runny nose, or sneezing; gooseflesh; increased sweating; increased yawning; loss of appetite; nausea or vomiting; nervousness, restlessness, or irritability; shivering or trembling; stomach cramps; trouble in sleeping; unusually large pupils of eyes; weakness

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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Fentanyl: Precautions


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