Brand Names : Zoladex, Zoladex 3-Month, Zoladex LA
- Gonadotropin-releasing hormone analog
- Antiendometriotic agent
- Gonadotropin inhibitor
Goserelin (GOE-se-rel-in) is a hormone similar
to the one normally released from the hypothalamus gland in the brain. It
is used to treat a number of medical problems. These include:
Cancer of the prostate in men
Cancer of the breast in women if it develops before or around the
time of menopause
Endometriosis, a painful condition caused by extra tissue growing
inside or outside of the uterus and
Thinning of the lining of the uterus before surgery on the uterus
When given regularly as an implant, goserelin works every day to decrease
the amount of estrogen and testosterone in the blood.
Reducing the amount of estrogen in the body is one way of treating endometriosis
and cancer of the breast, and can help thin the uterus lining before surgery.
Goserelin prevents the growth of tissue associated with endometriosis in adult
women during treatment and for up to 6 months after treatment is discontinued.
Reducing the amount of testosterone in the body is one way of treating
cancer of the prostate.
Suppressing estrogen can thin the bones or slow their growth. This is a
problem for adult women whose bones are no longer growing like the bones of
children. This is why goserelin is used only for up to 6 months in adult women
treated for endometriosis.
Goserelin is to be given only by or under the supervision of your doctor.
It is injected under the skin and is available in the following dosage form:
Implants (U.S. and Canada)
Some commonly used brand names are:
In the U.S. -
In Canada -