Headache Medicines, Ergot Derivative-Containing (Systemic)
Precautions While Using This Medicine
Check with your doctor
If your migraine headaches are worse than they were before you started
using this medicine, or your headache medicine stops working as well as it
did when you first started using it. This may mean that you are in danger
of becoming dependent on the headache medicine. Do not
try to get better relief by increasing the dose
If your migraine headaches are occurring more often than they did
before you started using this medicine. This is especially important if a
new headache occurs within 1 day after you took your last dose of headache
medicine, or if you are having headaches every day. This may mean that you
are dependent on the headache medicine. Continuing to
take this medicine will cause even more headaches later on
. Your doctor
can give you advice on how to relieve the headaches.
Drinking alcoholic beverages can make headaches worse or cause new headaches
to occur. People who suffer from severe headaches should probably avoid alcoholic
beverages, especially during a headache.
Smoking or nicotine replacement therapy products may increase some of
the harmful effects of dihydroergotamine or ergotamine. It is best to avoid
smoking or the use of nicotine replacement therapy products for several hours
after taking these medicines.
Dihydroergotamine and ergotamine may make you more sensitive to cold temperatures,
especially if you have blood circulation problems. They tend to decrease blood
flow in the skin, fingers, and toes. Dress warmly during cold weather and
be careful during prolonged exposure to cold temperatures. This is especially
important for older patients, who are more likely than younger adults to already
have problems with their circulation.
If you have a serious infection or illness of any kind, check with your
doctor before using this medicine, since you may be more sensitive to its
For patients taking one of the combination medicines that contains caffeine
Caffeine may interfere with the results of a test that uses dipyridamole
(e.g., Persantine) to help find out how well your blood is flowing through
certain blood vessels. You should not have any caffeine for at least 12 hours
before the test.
Caffeine may also interfere with some other laboratory tests. Before having
any other laboratory tests, tell the person in charge if you have taken a
medicine that contains caffeine.
For patients taking one of the combination medicines that contains belladonna alkaloids, dimenhydrinate, diphenhydramine, or pentobarbital
These medicines may cause some people to have blurred vision or to
become drowsy, dizzy, lightheaded, or less alert than they are normally. These
effects may be especially severe if you also take CNS depressants (medicines
that slow down the nervous system, possibly causing drowsiness) together with
one of these combination medicines. Some examples of CNS depressants are antihistamines
or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers,
or sleeping medicine; prescription pain medicine or narcotics; barbiturates;
medicine for seizures; muscle relaxants; and antiemetics (medicines that prevent
or relieve nausea or vomiting). If you are not able to lie down for a while,
make sure you know how you react to this medicine or
combination of medicines before you drive, use machines, or do anything else
that could be dangerous if you are dizzy or are not alert and able to see
Belladonna alkaloids, dimenhydrinate, and diphenhydramine may cause
dryness of the mouth, nose, and throat. For temporary relief of mouth dryness,
use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva
Belladonna alkaloids may interfere with certain laboratory tests
that check the amount of acid in your stomach. They should not be taken for
24 hours before the test.
Dimenhydrinate and diphenhydramine may interfere with skin tests
that show whether you are allergic to certain substances. They should not
be taken for 3 days before the test.