Isotretinoin : Side Effects (Accutane, Accutane Roche)

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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Isotretinoin : Side Effects

Isotretinoin (Systemic)

Brand Names : Accutane, Accutane Roche

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Bone or joint pain; burning, redness, itching, or other signs of eye inflammation; difficulty in moving; nosebleeds; scaling, redness, burning, pain, or other signs of inflammation of lips; skin infection or rash

Rare

Abdominal or stomach pain (severe); attempts at suicide or thoughts of suicide (usually stops after medicine is stopped); back pain; bleeding or inflammation of gums; blurred vision or other changes in vision; changes in behavior; decreased vision after sunset or before sunrise (sudden or may continue after medicine is stopped); diarrhea (severe); headache (severe or continuing); mental depression; nausea and vomiting; pain or tenderness of eyes; pain, tenderness, or stiffness in muscles (long-term treatment); rectal bleeding; yellow eyes or skin

Incidence not determined

Attack, assault, or use of force; black, tarry stools; bleeding from sore in mouth; bloating; bloody or cloudy urine; bloody cough; bone pain, tenderness, or aching; burning or stinging of skin; chest pain; chills; confusion; constipation; convulsions; cough or hoarseness; dark-colored urine; decrease in height; difficulty breathing; difficulty in speaking; difficulty in swallowing; discharge from eye; dizziness; double vision; ear pain; excessive tearing; fainting; fast, irregular, pounding, or racing heartbeat or pulse; fever with or without chills; fractures and/or delayed healing; general feeling of discomfort or illness; heartburn; high blood pressure; hives; inability to move arms, legs, or facial muscles; inability to speak; indigestion; inflamed tissue from infection; irregular yellow patch or lump on skin; irritation; joint pain, redness, stiffness, or swelling; killing oneself; lack or slowing of normal growth in children; loosening of the fingernails; loss of appetite; loss of bladder control; loss or change in hearing; muscle cramps or spasms; muscle spasm or jerking of all extremities; muscle weakness; noisy breathing; pain in ribs, arms, or legs; pain or burning in throat; pain or tenderness around eyes and cheekbones; painful cold sores or blisters on lips, nose, eyes, or genitals; painful or difficult urination; pains in chest, groin, or legs, especially calves of legs; pains in stomach, side, or abdomen, possibly radiating to the back; pale skin; pinpoint red spots on skin; redness or soreness around fingernails; redness, soreness or itching skin; sensitivity of eyes to sunlight; shortness of breath; skin rash; slow speech; sneezing; sore throat; sores, ulcers, or white spots on lips or tongue or inside the mouth; sores, welting or blisters; stuffy or runny nose; sudden loss of coordination; sudden loss of consciousness; sudden onset of shortness of breath for no apparent reason; sudden onset of severe acne on chest and trunk; sudden onset of slurred speech; swelling of eyelids, face, lips, hands, lower legs, or feet; swollen, painful or tender lymph glands in neck, armpit, or groin; tightness in chest; unusual bleeding or bruising; unusual tiredness or weakness; unusual weight gain or loss; use of extreme physical or emotional force; watery or bloody diarrhea; wheezing

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Crusting of skin; difficulty in wearing contact lenses (may continue after medicine is stopped); dryness of eyes (may continue after treatment is stopped); dryness of mouth or nose; dryness or itching of skin; headache (mild); increased sensitivity of skin to sunlight; peeling of skin on palms of hands or soles of feet; stomach upset; thinning of hair (may continue after treatment is stopped)

Incidence not determined

Abnormal menstruation; burning, crawling, itching, numbness, prickling, �pins and needles� or tingling feeling; changes in fingernails or toenails; continuing ringing or buzzing or other unexplained noise in ears; dandruff; darkening of skin; fatigue; flushing; hair abnormalities; hair loss; increased hair growth, especially on the face; large amount of triglyceride in the blood; lightening of normal skin color; lightening of treated areas of dark skin; nervousness; oily skin; redness of face; severe sunburn; skin rash, encrusted, scaly and oozing; sleeplessness; stomach burning; sweating; trouble sleeping; unable to sleep; unusual drowsiness, dullness, tiredness, weakness or feeling of sluggishness; unusually warm skin of face; voice changes

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

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