Metoclopramide (Systemic)
Brand Names : Octamide, Metoclopramide Intensol, Reglan, Apo-Metoclop, Maxeran, PMS-Metoclopramide
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For metoclopramide,
the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to metoclopramide, procaine, or procainamide. Also tell
your health care professional if you are allergic to any other substances,
such as foods, preservatives, or dyes.
Pregnancy - Not enough studies have been done in humans to determine
metoclopramide's safety during pregnancy. However, metoclopramide has not
been shown to cause birth defects or other problems in animal studies.
Breast-feeding - Metoclopramide passes into the breast milk and
may cause unwanted effects in nursing babies. Be sure you have discussed the
risks and benefits of the medicine with your doctor.
Children - Muscle spasms, especially of jaw, neck, and back,
and tic-like (jerky) movements of head and face may be especially likely to
occur in children, who are usually more sensitive than adults to the effects
of metoclopramide. Premature and full-term infants may develop blood problems
if given high doses of metoclopramide.
Older adults - Shuffling walk and trembling and shaking of hands
may be especially likely to occur in elderly patients after they have taken
metoclopramide over a long time.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
metoclopramide, it is especially important that your health care professional
know if you are taking the following:
-
Central nervous system (CNS) depressants (medicine that causes drowsiness) - Use
with metoclopramide may cause severe drowsiness
Other medical problems - The presence of other medical
problems may affect the use of metoclopramide. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Abdominal or stomach bleeding or
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Asthma or
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High blood pressure or
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Intestinal blockage or
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Mental depression or
-
Parkinson's disease - Metoclopramide may make these conditions
worse
-
Epilepsy - Metoclopramide may increase the risk of having a seizure
-
Kidney disease (severe) - Higher blood levels of metoclopramide
may result, possibly increasing the chance of side effects
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