Oxaliplatin (Systemic)

Brand Names : Eloxatin

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

More common

Abnormal tongue sensation; black, tarry stools; bleeding gums; blood in urine or stools; blistering, peeling, redness, and/or swelling of palms of hands or bottoms of feet; burning, prickling, itching, or tingling of skin; chest pain; chills; confusion; cough; decreased feeling, or pain in the hands, feet, around mouth, or throat; decreased urination; difficult breathing; difficulty in articulating words; difficulty in moving; difficulty performing daily activities such as writing, buttoning, swallowing or walking; difficulty swallowing; dizziness; dry mouth; eye pain; fainting; fever; increase in heart rate; jaw spasm; lightheadedness; muscle pain or stiffness; numbness; numbness, pain, tingling, or unusual sensations in palms of hands or bottoms of feet; pain in chest, groin, or legs, especially the calves; pain in joints; painful or difficult urination; pale skin; pinpoint red spots on skin; rapid breathing; sensation of pins and needles; severe, sudden headache; shortness of breath; slurred speech; sore throat; sores, ulcers, or white spots on lips or in mouth; stabbing pain; sudden loss of coordination; sudden, severe weakness or numbness in arm or leg; sudden, unexplained shortness of breath; sunken eyes; swelling; swelling or inflammation of the mouth; swollen glands; thirst; troubled breathing with exertion; unusual bleeding or bruising; unusual tiredness or weakness; vision changes; wrinkled skin

Less common

Convulsions; fast heartbeat; hives; increased thirst; irregular heartbeat; itching; loss of appetite; mood changes; nausea or vomiting; numbness or tingling in hands, feet, or lips; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; skin rash; tightness in chest; wheezing

Symptoms of Overdose

Get emergency help immediately if any of the following symptoms of overdose occur

Agitation; black, tarry stools; bleeding gums; blood in urine or stools; burning, prickling, itching, or tingling of skin; chest pain or discomfort; coma; confusion; cough or hoarseness; diarrhea; difficult urination; disorientation; dizziness or fainting; fever or chills; involuntary, rapid, rhythmic movement of the eyes; lack of coordination; lack of sensation; lethargy; lightheadedness; lower back or side pain; muscle twitching; paralysis; pinpoint red spots on skin; respiratory failure; seizures; severe weakness; shortness of breath; slow or irregular heartbeat; slurred speech; tremors; unusual tiredness; unusual bleeding or bruising; vomiting, profuse; wheezing

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your healthcare professional if any of the following side effects continue or are bothersome.

More Common

Abdominal pain; acid or sour stomach; back pain; belching; body aches or pain; diarrhea; ear congestion; feeling unusually cold shivering; headache; heartburn; indigestion; loss of appetite; loss of voice; nasal congestion; nausea; runny nose; sleeplessness; sneezing; sore throat; stomach discomfort, upset or pain; stuffy nose; trouble sleeping; unable to sleep; weight loss

Less common

Bad, unusual or unpleasant (after) taste; bloated, full feeling; bloating or swelling of face, arms, hands, lower legs, or feet; bloody nose; burning while urinating; change in taste; cracked lips; congestion; dryness or soreness of throat; excess air or gas in stomach or intestines; feeling of warmth; hoarseness; passing gas; rapid weight gain; redness of the face, neck, arms and occasionally upper chest; tender, swollen glands in neck; tingling of hands or feet; trouble in swallowing; unusual tearing of eyes; voice changes; vomiting

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Hair loss; thinning of hair

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your healthcare professional.