Pralidoxime (Systemic)
Brand Names : Protopam Chloride, 2-PAM, 2-PAM chloride
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For pralidoxime, the
following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to pralidoxime. Also tell your health care professional
if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Studies on effects in pregnancy have not been done
in either humans or animals.
Breast-feeding - It is not known whether pralidoxime passes into
breast milk. Although most medicines pass into breast milk in small amounts,
many of them may be used safely while breast-feeding. Mothers who are taking
this medicine and who wish to breast-feed should discuss this with their doctor.
Children - Although there is no specific information comparing
use of pralidoxime in children with use in other age groups, this medicine
is not expected to cause different side effects or problems in children than
it does in adults.
Older adults - Many medicines have not been studied specifically
in older people. Therefore it may not be known whether they work exactly the
same way they do in younger adults or if they cause different side effects
or problems in older people. There is no information comparing use of pralidoxime
in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are using
pralidoxime, it is especially important that your health care professional
know if you are taking any of the following:
-
Aminophylline (e.g., Somophyllin) or
-
Caffeine (e.g., NoDoz) or
-
Theophylline (e.g., Theo-Dur, Somophyllin-T) - These medicines
may make the effects of the poisoning worse
Other medical problems - The presence of other medical
problems may affect the use of pralidoxime. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Kidney disease - The effects of this medicine may be increased
-
Myasthenia gravis - This medicine may make the condition worse
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