Brand Names : Benemid, Probalan, Benuryl
Proper Use of This Medicine
upsets your stomach, it may be taken with food. If this does not work, an
antacid may be taken. If stomach upset (nausea, vomiting, or loss of appetite)
continues, check with your doctor.
For patients taking probenecid for gout
After you begin to take probenecid, gout attacks may continue to
occur for a while. However, if you take this medicine regularly as directed
by your doctor, the attacks will gradually become less frequent and less painful
than before. After you have been taking probenecid for several months, they
may stop completely.
This medicine will help prevent gout attacks but it will not relieve
an attack that has already started. Even if you take
another medicine for gout attacks, continue to take this medicine also
If you have any questions about this, check with your doctor.
For patients taking probenecid for gout or to help
remove uric acid from the body
When you first begin taking probenecid, the amount of uric acid in
the kidneys is greatly increased. This may cause kidney stones or other kidney
problems in some people. To help prevent this, your doctor may want you to
drink at least 10 to 12 full glasses (8 ounces each) of fluids each day, or
to take another medicine to make your urine less acid. It is important that
you follow your doctor's instructions very carefully.
Dosing - The dose of probenecid will be different for
different patients. Follow your doctor's orders or the
directions on the label
. The following information includes only the
average doses of probenecid. If your dose is different,
do not change it
unless your doctor tells you to do so.
For treating gout or removing uric acid from
Adults: 250 mg (one-half of a 500-mg tablet) two times a day for
about one week, then 500 mg (one tablet) two times a day for a few weeks.
After this, the dose will depend on the amount of uric acid in your blood
or urine. Most people need 2, 3, or 4 tablets a day, but some people may need
Children: It is not likely that probenecid will be needed to treat
gout or to remove uric acid from the body in children. If a child needs this
medicine, however, the dose would have to be determined by the doctor.
For helping antibiotics work better
Adults: The amount of probenecid will depend on the condition being
treated. Sometimes, only one dose of 2 tablets is needed. Other times, the
dose will be 1 tablet four times a day.
Children: The dose will have to be determined by the doctor. It depends
on the child's weight, as well as on the condition being treated. Older children
and teenagers may need the same amount as adults.
Missed dose - If you are taking probenecid regularly and you
miss a dose, take the missed dose as soon as possible. However, if you do
not remember until it is almost time for the next dose, skip the missed dose
and go back to your regular dosing schedule. Do not double doses.
Storage - To store this medicine:
Keep out of the reach of children.
Store away from heat and direct light.
Do not store this medicine in the bathroom, near the kitchen sink,
or in other damp places. Heat or moisture may cause the medicine to break
Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.