Pyrazinamide (Systemic)

Brand Names : pms-Pyrazinamide, Tebrazid

Proper Use of This Medicine

To help clear up your TB completely, it is important that you keep taking this medicine for the full time of treatment , even if you begin to feel better after a few weeks. It is important that you do not miss any doses .

Dosing - The dose of pyrazinamide will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of pyrazinamide. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage form (tablets):
  • For tuberculosis (TB):
    • Adults and children - Dose is based on body weight. The usual dose is 15 to 30 milligrams (mg) of pyrazinamide per kilogram (kg) (6.8 to 13.6 mg per pound) of body weight once a day; or 50 to 70 mg per kg (22.7 to 31.8 mg per pound) two times a week or three times a week, depending on the schedule your doctor chooses for you. This medicine must be taken along with other medicines used to treat TB.

Missed dose - If you do miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.