Brand Names : Elitek, Fasturtec
Before Using This Medicine
to use a medicine, the risks of using the medicine must be weighed against
the good it will do. This is a decision you and your doctor will make. For
rasburicase, the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to rasburicase. Also tell your doctor and pharmacist
if you are allergic to any other substances, such as foods, preservatives,
dyes, fungi or yeasts. Tell your doctor if you have chest pain, trouble breathing,
dizziness or lightheadedness, hives or skin rash during treatment with rasburicase.
Pregnancy - Studies on the effects in pregnancy have not been
done in either animals or humans. Before taking this medicine, make sure your
doctor knows if you are pregnant or if you may become pregnant.
Breast-feeding - It is not known whether rasburicase passes into
breast milk. Mothers who are taking this medicine and wish to breast feed
should discuss this with their health care professional.
Children - This medicine has been tested in children (1 month
to 17 years of age). Children less than 2 years of age may be at increased
risk for adverse effects.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work the same
way that they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing the
use of rasburicase in the elderly with use in other age groups.
Patients of African or Mediterranean ancestry should be tested for
glucose 6 phosphate dehydrogenase (G6PD) deficiency. These patients may be
at increased risk for severe hemolysis.
Other medical problems - The presence of other medical problems may
affect the use of rasburicase. Make sure you tell your doctor if you have
any other medical problems, especially:
Anaphylaxis, hypersensitivity reaction, or a sudden, severe allergic
reaction (or history of) or
Glucose-6-phosphate dehydrogenase (G6PD) deficiency (a hereditary
metabolic disorder affecting red blood cells) or
Hemolytic reactions (or history of) or
Methemoglobinemia reactions (or history of) - Rasburicase should
not be used if you have or have had any of these medical problems
Tumor lysis syndrome, risk of - Fluids may be injected into the