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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Butorphanol (Nasal)

Butorphanol (Into The Nose)

Butorphanol (byoo-TOR-fa-nole)

Treats pain.

Brand Name(s):

Stadol NS
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to butorphanol.

How to Use This Medicine:


  • Your doctor will tell you how much to use and how often.
  • Blow your nose gently to clear the nostrils.
  • Take the cap off of the bottle and remove the clip from the neck of the pump.
  • If you are using the medicine for the first time, you will need to prime the spray pump.
  • To do this, hold the spray bottle with your thumb on the bottom of the bottle and your index and middle fingers on the 2 flaps on the side of the pump.
  • Push down with your index and middle fingers. Keep pumping until you see the medicine spray from the bottle.
  • Put the tip of the spray pump into your nostril.
  • Close the other nostril with your finger and lean your head slightly forward.
  • Sniff gently and push down on the 2 flaps to spray the medicine into your nose. Keep your mouth closed as you are breathing in.
  • Take the spray pump out of your nostril and tilt your head back. Sniff a few more times.

If a dose is missed:

  • Use the spray as soon as you remember that you missed a dose.
  • If it is almost time for your next usual dose, wait until then to use your medicine and skip the missed dose.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store the medicine at room temperature away from heat. Do not freeze.
  • Keep all medicine out of the reach of children.
  • When the medicine is gone, rinse the used pump and bottle with water. Throw the parts away where children cannot get to them.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are taking cimetidine (Tagamet®, erythromycin, theophylline, other nasal sprays (such as Afrin® or Dristan®), or any drug that could make you sleepy such as sleeping pills, cold and allergy medicine, muscle relaxants, or narcotic pain killers.
  • Avoid drinking alcohol while you are using this medicine.
Warnings While Using This Medicine:

  • Check with your doctor before taking butorphanol if you have asthma, liver, kidney, or heart disease; a history of drug abuse; any lung problems.
  • If you are pregnant or breastfeeding, talk to your doctor before taking this medicine.
  • This medicine may make you drowsy or dizzy. Be careful if you are driving a car or using machinery.
  • This medicine may be habit-forming. You should not use more of it than your doctor ordered.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Fast or irregular heartbeat
  • Trouble breathing
  • Confusion or hallucinations
  • Trouble urinating
  • Seizures

If you notice these less serious side effects, talk with your doctor:

  • Drowsiness or dizziness
  • Nausea or vomiting
  • Nasal congestion
  • Constipation
  • Trouble sleeping
  • Ringing in the ears
  • Bad taste in the mouth
  • Blurred vision
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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