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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Guaifenesin (Oral)

Guaifenesin (By Mouth)

Guaifenesin (gwye-FEN-e-sin)

Treats cough due to colds, the flu, or other conditions. Guaifenesin is an expectorant that loosens mucus in your lungs.

Brand Name(s):

Guaifenex LA, Guaifenex G, Amibid LA, Robitussin, Mucinex, Bidex 400, Allfen JR, Organidin NR, Organ-1 NR, GG-200 NR, Iofen, Hytuss, Hytuss 2x, Iofen-NF, Ganidin NR
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to guaifenesin.

How to Use This Medicine:

Capsule, Tablet, Long Acting Capsule, Long Acting Tablet, Liquid

  • Your doctor will tell you how much medicine to take and how often. Drink a full glass of water after each dose; drink plenty of fluids during the day. May be taken with or without food.
  • Measure the oral liquid medicine with a marked measuring spoon or medicine cup.
  • Do not chew or crush the tablet or capsule. Swallow whole with a full glass of water.
  • Swallow the sprinkle capsule whole, or open the capsule and mix the medicine beads with soft food (applesauce or pudding). Swallow the mixture whole; do not chew.

If a dose is missed:

  • May be taken as soon as possible; however, missing one dose is usually not a problem.
  • Skip the missed dose if it is almost time for your next dose
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store in a tight container at room temperature, away from heat and moisture. Do not freeze the oral liquid.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:


Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.


Warnings While Using This Medicine:

  • Some guaifenesin syrups contain alcohol.
  • If you have asthma, emphysema, or a chronic cough from smoking, talk to your doctor before taking this medicine.
  • If you are pregnant or breastfeeding check with your doctor or pharmacist before taking this medicine.
Possible Side Effects While Using This Medicine:

If you notice these less serious side effects, talk with your doctor:

  • Nausea, vomiting, diarrhea, stomach pain
  • Drowsiness
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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