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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Propafenone Hydrochloride (Oral)

Propafenone Hydrochloride (By Mouth)

Propafenone Hydrochloride (proe-pa-FEEN-one hye-droe-KLOR-ide)

Treats an irregular heartbeat (arrhythmia). Belongs to a class of drugs called class antiarrhythmics.

Brand Name(s):

Rythmol, Rythmol SR
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to propafenone.

How to Use This Medicine:

Tablet, Long Acting Capsule

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
  • Take this medicine exactly as your doctor ordered, even if you feel fine.
  • You may take this medicine with or without food.Swallow the extended-release capsule whole. Do not crush, break, or chew it.
  • You may need to carry identification stating that you are using propafenone. Ask your doctor about this.

If a dose is missed:

  • Take the missed dose as soon as you can, unless you are more than 4 hours late.
  • If you are more than 4 hours late, skip the missed dose and take your medicine at your usual time.
  • You should not use two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
  • Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.
  • Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are using other heart medicine (such as Lanoxin®, Cordarone®, or Cardizem®), or a blood thinner such as Coumadin®.
Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, asthma, bronchitis, emphysema, or a recent heart attack.
  • Do not suddenly stop taking this medicine without asking your doctor.
  • This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Fast heartbeat
  • Chest pain
  • Shortness of breath or trouble breathing
  • Fainting
  • Swelling of the feet or ankles
  • Blurred vision
  • Unexplained fever, chills, or sore throat
  • Skin rash, severe itching or hives

If you notice these less serious side effects, talk with your doctor:

  • Dizziness, light-headedness, or hot flashes
  • Headache
  • Nausea, vomiting, or heartburn
  • Dry mouth or metallic or bitter taste
  • Diarrhea or constipation
  • Stomach cramps or loss of appetite
  • Trembling or shaking
If you notice other side effects that you think are caused by this medicine, tell your doctor.

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