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You are here : 3-RX.com > Drugs & Medications > Quick Drug Information (DrugNotes) > Sulfacetamide Sodium/Sulfur (Topical)

Sulfacetamide Sodium/Sulfur (On The Skin)

Sulfacetamide Sodium (sul-fa-SEE-ta-mide SOE-dee-um), Sulfur (SUL-fyoor)

Treats acne and seborrheic dermatitis (scaly areas on the skin).

Brand Name(s):

Plexion, Plexion TS, Plexion Sct, Sulfacet-R, Zetacet, Nicosyn, AVAR Cleanser, Rosula, Rosanil, Rosac Cream w/Sunscreens, Clenia, AVAR-e, AVAR-e Green, AVAR Gel, AVAR Green
There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not use this medicine if you have ever had an allergic reaction to sulfa drugs (such as Bactrim®), diabetes medicine (such as Diabenase®, Orinase®), sulfur, or sulfites.

How to Use This Medicine:

Lotion, Cream, Suspension, Gel/Jelly, Soap

  • Your doctor will tell you how much to use and how often.
  • For use only on the skin.
  • Clean the affected area well.
  • Wait 30 minutes after washing or shaving to put on this medicine.
  • Wash your hands with soap and water before and after using this medicine.
  • Shake well before each use.
  • Using your fingertips, apply the medicine lightly on and around the acne.
  • Do not put the lotion in or around your eyes or mouth.
  • This medicine should come with a color blender which allows you to change the color of the lotion to match your skin color.

If a dose is missed:

  • If you miss a dose, apply it as soon as you remember.
  • If it is almost time for your next regularly scheduled dose, skip the missed dose and continue with your regular schedule.
  • Do not apply two doses at the same time.
How to Store and Dispose of This Medicine:

  • Store this medicine at room temperature, away from heat and direct light.
  • After 4 months, throw away any medicine you have not used.
  • Keep all medicine out of the reach of children.
Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Unless approved by your doctor, You should not use other creams, lotions, or medicines on your skin, including sunscreen, and cosmetics (make-up) that contains alcohol.
Warnings While Using This Medicine:

  • Talk to your doctor before using this medicine if you are pregnant or breastfeeding.
  • Avoid other sources of skin irritation during use (such as sunlight, tanning beds, or sunlamps) unless approved by your doctor.
  • Check with your doctor before using this medicine if you have kidney problems.
Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Skin rash, or itching
  • Severe skin swelling, burning, or blistering

If you notice these less serious side effects, talk with your doctor:

  • Peeling of skin
  • Mild stinging
  • Redness
If you notice other side effects that you think are caused by this medicine, tell your doctor.


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