Guillain-Barre Syndrome
Alternate Names : Landry-Guillain-Barré Syndrome
What are the treatments for the condition?
Initial treatment of GBS focuses on life support. A ventilator, or artificial breathing
machine, may be needed. Fluids can be given through an intravenous line. Food can be given through a
tube into the stomach.
A procedure called plasmapheresis can be effective if used early in
the course of the illness. Plasmapheresis removes antibodies that may be
present in the bloodstream. It also provides the person with fluids or plasma
that is free of the antibodies that trigger GBS.
Immunoglobulin therapy is also used to treat GBS. High
doses of immunoglobulins, or proteins from the immune system of normal donors,
are given to the person with GBS. For some unknown reason, these globulins
reduce the body's attack on its own nerves.
Corticosteroids, such as methylprednisolone, are sometimes given together with
plasmapheresis or immune serum globulin. However, their effectiveness is
questionable, and they may worsen the disease.
What are the side effects of the treatments?
Plasmapheresis is associated with a small risk of getting
bloodborne infectious diseases. Corticosteroids and immune globulins may
increase the person's risk for many types of infection.
What happens after treatment for the condition?
Physical
therapy may be ordered to prevent contractures and other
complications. Along with
occupational therapy, it can be helpful in restoring the person's
normal level of function. Pain
medicines and physical therapy may be needed if the person has
chronic pain.
How is the condition monitored?
After the acute phase of GBS, the individual will have regular
visits with the healthcare provider. Any new or worsening symptoms should be
reported to the provider.
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