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You are here : 3-RX.com > Medical Encyclopedia > Diseases and Conditions > Histiocytosis: Treatment & Monitoring


Alternate Names : Pulmonary Histiocytosis X, Histiocytosis X, Eosinophilic Granuloma, Nonlipid Reticuloendotheliosis, Langerhans Histiocytoses, Letterer-Siwe Disease, Hand-Schuller-Christian Disease, Pulmonary Langerhans' Granulomatosis

Histiocytosis | Symptoms & Signs | Diagnosis & Tests | Prevention & Expectations | Treatment & Monitoring

What are the treatments for the condition?

Histiocytosis is treated with corticosteroids, such as prednisone and methotrexate. These help reduce inflammation in the lungs. Other medications, such as cyclophosphamide, may also be tried. However, no therapy clearly helps this disease. Sometimes radiation therapy is used to treat bone lesions. A person who smokes should stop smoking.

What are the side effects of the treatments?

Side effects vary depending on the medication, but may include allergic reactions.

What happens after treatment for the condition?

Complications can occur with histiocytosis. A sudden collapse of the lung, known as atelectasis, is common. This disorder can lead to death due to lung or heart failure.

How is the condition monitored?

A series of x-rays and pulmonary function tests may be needed to see how the histiocytosis changes over time. Any new or worsening symptoms should be reported to the healthcare provider.

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Histiocytosis: Prevention & Expectations


Author: James Broomfield, MD
Reviewer: Gail Hendrickson, RN, BS
Date Reviewed: 07/02/01

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