Antifungals, Azole (Vaginal)

Proper Use of This Medicine

Vaginal azoles usually come with patient directions. Read them carefully before using this medicine.

Use this medicine at bedtime, unless otherwise directed by your doctor. The vaginal tampon form of miconazole should be left in the vagina overnight and removed the next morning.

This medicine is usually inserted into the vagina with an applicator. However, if you are pregnant, check with your doctor before using the applicator.

Some of the vaginal suppositories or tablets come packaged with a small tube of cream. This cream can be applied outside of the vagina in the genital area to treat itching. The packages are called combination, dual, or twin packs.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment , even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses . Also, do not stop using this medicine if your menstrual period starts during the time of treatment .

Dosing - The dose of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

For butoconazole
• For yeast infection:
  • For vaginal cream dosage form:
    • Adults and teenagers:
      • Women who are not pregnant: 100 milligrams (mg) (one full applicator) of 2% cream inserted into the vagina at bedtime for three nights in a row.
      • Pregnant women, after the third month: 100 mg (one full applicator) of 2% cream inserted into the vagina at bedtime for six nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For vaginal suppository dosage form:
    • Adults and teenagers:
      • Women who are not pregnant: 100 mg (one suppository) inserted into the vagina at bedtime for three nights in a row.
      • Children up to 12 years of age - Use and dose must be determined by your doctor.

For clotrimazole
• For yeast infection:
  • For vaginal cream dosage form:
    • Adults and teenagers - The dose depends on the strength of the cream.
      • 1% cream: 50 milligrams (mg) (one full applicator) inserted into the vagina at bedtime for six to fourteen nights in a row.
      • 2% cream: 100 mg (one full applicator) inserted into the vagina at bedtime for three nights in a row.
      • 10% cream: 500 mg (one full applicator) inserted into the vagina at bedtime for one night only.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For vaginal tablet dosage form:
    • Adults and teenagers - The dose depends on the strength of the vaginal tablet.
      • Women who are not pregnant:
        • 100-mg tablet: Insert one tablet into the vagina at bedtime for six or seven nights in a row.
        • 200-mg tablet: Insert one tablet into the vagina at bedtime for three nights in a row.
        • 500-mg tablet: Insert one tablet into the vagina at bedtime for one night only.
      • Pregnant women: 100 mg (one vaginal tablet) inserted into the vagina at bedtime for seven nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.

For econozole
• For yeast infection:
  • For vaginal suppository dosage form:
    • Adults and teenagers - 150 milligrams (mg) (one vaginal suppository) inserted into the vagina at bedtime for three nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.

For miconazole
• For yeast infection:
  • For vaginal cream dosage form:
    • Adults and teenagers - 20 milligrams (one full applicator) inserted into the vagina at bedtime for seven nights in a row. Treatment may be repeated if needed.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For vaginal suppository dosage form:
    • Adults and teenagers - The dose depends on the strength of the suppository.
      • 100-milligrams (mg) suppository: Insert one vaginal suppository into the vagina at bedtime for seven nights in a row. Treatment may be repeated if needed.
      • 200-mg suppository or
      • 400-mg suppository: Insert one vaginal suppository into the vagina at bedtime for three nights in a row. Treatment may be repeated if needed.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For tampon dosage form:
    • Adults and teenagers - 100 mg (one tampon) inserted into the vagina at bedtime and then removed the next morning. This is repeated every night for five nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.

For terconazole
• For yeast infection:
  • For vaginal cream dosage form:
    • Adults and teenagers - The dose depends on the strength of the cream.
      • 0.4% cream: 20 milligrams (mg) (one full applicator) inserted into the vagina at bedtime for seven nights in a row.
      • 0.8% cream: 40 mg (one full applicator) inserted into the vagina at bedtime for three nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For vaginal suppository dosage form:
    • Adults and teenagers - 80 mg (one vaginal suppository) inserted into the vagina at bedtime for three nights in a row.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.

For tioconazole
• For yeast infection:
  • For vaginal ointment dosage form:
    • Adults and teenagers - 300 milligrams (mg) (one full applicator) of 6.5% ointment inserted into the vagina at bedtime for one night only.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.
  • For vaginal suppository dosage form:
    • Adults and teenagers - 300 mg (one vaginal suppository) inserted into the vagina at bedtime for one night only.
    • Children up to 12 years of age - Use and dose must be determined by your doctor.

Missed dose - If you miss a dose of this medicine, insert it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store the vaginal suppository or vaginal tablet form of this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Keep the vaginal cream, ointment, and suppository forms of this medicine from freezing.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.