Bismuth Subsalicylate, Metronidazole, and Tetracycline—For H. pylori (Systemic)
Brand Names : Helidac
Proper Use of This MedicineThis combination
of medicines (bismuth subsalicylate, metronidazole, and tetracycline) comes
with instructions for the patient included in the package. Make sure you read
and understand the instructions, or ask your health care professional if you
need additional information or explanation. It is important that you understand
and follow the instructions exactly.
Also, it is important that you complete the full course of therapy with
this combination of medicines to help clear up the infection from H. pylori
related to your ulcer.
Dosing - Each day's therapy is packaged on a blister
card that contains eight chewable tablets (each containing 262.4 milligrams
[mg] of bismuth subsalicylate), four tablets (each containing 250 mg of metronidazole),
and four capsules (each containing 500 mg of tetracycline).
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For oral
dosage forms (blister card containing
chewable tablets, tablets, and capsules):
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For the treatment of ulcers related to infection with H. pylori
:
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Adults - For each dose of this combination of medicines:
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Chew and swallow two tablets of bismuth subsalicylate (525 mg)
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Swallow one tablet of metronidazole (250 mg)
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Swallow one capsule of tetracycline (500 mg)
Be sure to swallow the tablet of metronidazole and the capsule of tetracycline
with a full glass (eight ounces) of water. This will help prevent irritation
of the esophagus (tube between the throat and stomach) or stomach. Each dose of this combination of medicines (bismuth subsalicylate, metronidazole,
and tetracycline) is taken four times a day, with meals and at bedtime, for
fourteen days. Your doctor will also prescribe for you another medicine, a
histamine H 2
-receptor antagonist, which will
come with its own directions and must be taken along with this combination
of medicines
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Children - Use and dose must be determined by your doctor.
Missed dose - If you miss a dose of this combination of medicines,
skip the missed dose and go back to your regular dosing schedule. Do not double
doses. If you miss more than four doses of this combination of medicines,
check with your doctor.
Storage - To store this combination of medicines:
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Keep out of the reach of children.
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Store away from heat and direct light.
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Do not store in the bathroom, near the kitchen sink, or in other
damp places. Heat or moisture may cause these medicines to break down.
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Keep these medicines from freezing. Do not refrigerate.
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Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.
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