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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Butalbital and Acetaminophen

Butalbital and Acetaminophen (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

  • Analgesic

Butalbital and acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen) combination is a pain reliever and relaxant. It is used to treat tension headaches. Butalbital belongs to the group of medicines called barbiturates (bar-BI-tyoo-rates) . Barbiturates act in the central nervous system (CNS) to produce their effects.

When you take butalbital for a long time, your body may get used to it so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine. In patients who get headaches, the first symptom of withdrawal may be new (rebound) headaches.

Some butalbital and acetaminophen combinations also contain caffeine (KAF-een). Caffeine may help to relieve headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

Butalbital and acetaminophen combination may also be used for other kinds of headaches or other kinds of pain as determined by your doctor.

Butalbital and acetaminophen combinations are available only with your doctor's prescription in the following dosage forms:

  • Butalbital and Acetaminophen
    • Capsules (U.S.)
    • Tablets (U.S.)
  • Butalbital, Acetaminophen, and Caffeine
    • Capsules (U.S.)
    • Tablets (U.S.)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Amaphen 2
  • Anolor-300 2
  • Anoquan 2
  • Arcet 2
  • Bancap 1
  • Bucet 1
  • Butace 2
  • Conten 1
  • Dolmar 2
  • Endolor 2
  • Esgic 2
  • Esgic-Plus 2
  • Ezol 2
  • Femcet 2
  • Fioricet 2
  • Isocet 2
  • Medigesic 2
  • Pacaps 2
  • Pharmagesic 2
  • Phrenilin 1
  • Phrenilin Forte 1
  • Repan 2
  • Sedapap 1
  • Tencet 2
  • Tencon 1
  • Triad 2
  • Triaprin 1
  • Two-Dyne 2


For quick reference, the following butalbital and acetaminophens are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Butalbital and Acetaminophen (byoo-TAL-bi-tal and a-seat-a-MIN-oh-fen)†‡
2. Butalbital, Acetaminophen, and Caffeine (byoo-TAL-bi-tal, a-seat-a-MIN-oh-fen, and KAF-een)†‡
† Not commercially available in Canada
‡ Generic name product may be available in the U.S.

† Not commercially available in Canada.


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Butalbital and Acetaminophen: Before Using

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