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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Capsaicin : Proper Use

Capsaicin (Topical)

Brand Names : Zostrix, Zostrix-HP

Capsaicin | Before Using | Proper Use | Precautions | Side Effects

Proper Use of This Medicine

If you are using capsaicin for the treatment of neuralgia caused by herpes zoster, do not apply the medicine until the zoster sores have healed.

It is not necessary to wash the areas to be treated before you apply capsaicin, but doing so will not cause harm.

Apply a small amount of cream and use your fingers to rub it well into the affected area so that little or no cream is left on the surface of the skin afterwards.

Wash your hands with soap and water after applying capsaicin to avoid getting the medicine in your eyes or on other sensitive areas of the body. However, if you are using capsaicin for arthritis in your hands, do not wash your hands for at least 30 minutes after applying the cream.

If a bandage is being used on the treated area, it should not be applied tightly.

When you first begin to use capsaicin, a warm, stinging, or burning sensation (feeling) may occur. This sensation is related to the action of capsaicin on the skin and is to be expected. Although this sensation usually disappears after the first several days of treatment, it may last 2 to 4 weeks or longer. Heat, humidity, clothing, bathing in warm water, or sweating may increase the sensation. However, the sensation usually occurs less often and is less severe the longer you use the medicine. Reducing the number of doses of capsaicin that you use each day will not lessen the sensation and may lengthen the period of time that you get the sensation. Also, reducing the number of doses you use may reduce the amount of pain relief that you get.

Capsaicin must be used regularly every day as directed if it is to work properly. Even then, it may not relieve your pain right away. The length of time it takes to work depends on the type of pain you have. In persons with arthritis, pain relief usually begins within 1 to 2 weeks. In most persons with neuralgia, relief usually begins within 2 to 4 weeks, although with head and neck neuralgias, relief may take as long as 4 to 6 weeks.

Once capsaicin has begun to relieve pain, you must continue to use it regularly 3 or 4 times a day to keep the pain from returning. If you stop using capsaicin and your pain returns, you can begin using it again.

Dosing - The dose of capsaicin may be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average dose of capsaicin. If your dose is different, do not change it unless your doctor tells you to do so.

  • For topical dosage form (cream):
    • For neuralgias or itching of the skin:
      • Adults and children 2 years of age or older - Apply regularly 3 or 4 times a day and rub well.
      • Children up to 2 years of age - Use and dose must be determined by your doctor.

Missed dose - If you miss a dose of this medicine, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage - To store this medicine:

  • Keep out of the reach of children.
  • Store away from heat and direct light.
  • Keep the medicine from freezing. Do not refrigerate.
  • Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

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Capsaicin: Precautions



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