Carboprost (Systemic)

Brand Names : Hemabate, Prostin/15M

Before Receiving This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For carboprost, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to carboprost or other oxytocics (medicines that stimulate the uterus to contract). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your doctor if you are taking any prescription or nonprescription (over-the-counter [OTC]) medicine.

Other medical problems - The presence of other medical problems may affect the use of carboprost. Make sure you tell your doctor if you have any other medical problems, especially:

• Adrenal gland disease (history of) - Carboprost stimulates the body to produce steroids

• Anemia - In some patients, abortion with carboprost may result in loss of blood that may require a transfusion

• Asthma (or history of) or
• Lung disease - Carboprost may cause narrowing of the blood vessels in the lungs or narrowing of the lung passages

• Diabetes mellitus (sugar diabetes) (history of)

• Epilepsy (or history of) - Rarely, seizures have occurred with use of carboprost

• Fibroid tumors of the uterus or
• Uterus surgery (history of) - There is an increased risk of rupture of the uterus

• Glaucoma - Rarely, the pressure within the eye has increased during use of carboprost

• Heart or blood vessel disease (or history of) or
• High blood pressure (or history of) or
• Low blood pressure (or history of) - Carboprost may cause changes in heart function or blood pressure changes

• Jaundice (history of)

• Kidney disease (or history of)

• Liver disease (or history of) - The body may not get carboprost out of the bloodstream at the usual rate, which may make the medicine work longer or cause toxic effects