Cisapride (Systemic)
Brand Names : Propulsid, Prepulsid
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For cisapride, the following
should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to cisapride. Also tell your health care professional if
you are allergic to any other substances, such as foods, preservatives, or
dyes.
Pregnancy - Cisapride has not been studied in pregnant women.
However, studies in animals have shown that cisapride causes harm to the fetus.
Before taking this medicine, make sure your doctor knows if you are pregnant
or if you may become pregnant.
Breast-feeding - Cisapride passes into breast milk and may cause
unwanted effects in nursing babies, particularly if the infant or mother are
taking certain other medicines. Be sure you have discussed the risks and benefits
of this medicine with your doctor.
Children - Cisapride can cause serious side effects in any
patient. Therefore, it is especially important that you discuss with the child's
doctor the good that this medicine may do, as well as the risks of using it.
Older adults - Elderly people are especially sensitive to the effects
of cisapride. Cisapride stays in the body longer so the dose may be different
than in younger people.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
cisapride, it is especially important that your health care professional know
if you are taking any of the following:
-
Amantadine (e.g., Symmetrel) or
-
Anticholinergics (medicine for abdominal or stomach spasms or cramps)
or
-
Antidepressants (medicine for depression) or
-
Antidyskinetics (medicine for Parkinson's disease or other conditions
affecting control of muscles) or
-
Antihistamines, except cetirizine (e.g., Reactine), and loratadine
(e.g., Claritin) or
-
Antipsychotics (medicine for mental illness) or
-
Buclizine (e.g., Bucladin) or
-
Carbamazepine (e.g., Tegretol) or
-
Cyclizine (e.g., Marezine) or
-
Cyclobenzaprine (e.g., Flexeril) or
-
Disopyramide (e.g., Norpace) or
-
Ipratropium (e.g., Atrovent) or
-
Meclizine (e.g., Antivert) or
-
Orphenadrine (e.g., Norflex) or
-
Oxybutynin (e.g., Ditropan) or
-
Promethazine (e.g., Phenergan) or
-
Trimeprazine (e.g., Temaril) - Cisapride may decrease the absorption
of these medicines and cause them to be less effective
-
Bepridil (e.g., Bepadin, Vascor) or
-
Bumetanide (e.g., Bumex) or
-
Clarithromycin (e.g., Biaxin) or
-
Erythromycin (e.g., E-Mycin) or
-
Ethacrynic acid (e.g., Edecrin) or
-
Fluconazole (e.g., Diflucan) or
-
Furosemide (e.g., Lasix) or
-
Indinavir (e.g., Crixivan) or
-
Itraconazole (e.g., Sporanox) or
-
Ketoconazole (e.g., Nizoral) or
-
Miconazole (e.g., Monistat i.v.) or
-
Nefazodone (e.g., Serzone) or
-
Nelfinivir (e.g., Viracept) or
-
Procainamide (e.g., Pronestyl) or
-
Quinidine (e.g., Quinidex) or
-
Ritonavir (e.g., Norvir) or
-
Saquinavir (e.g., Invirase) or
-
Sotalol (e.g., Betapace, Sotacor) or
-
Sparfloxacin (e.g., Zagam) or
-
Terodiline (e.g., Micturin) or
-
Troleandomycin (e.g., Tao) - These medicines may increase the
chance of serious side effects and should not be taken with cisapride
-
Diuretics (water pills) - These medicines may increase the chance
of serious side effects from cisapride
Other medical problems - The presence of other medical
problems may affect the use of cisapride. Make sure you tell your doctor if
you have any other medical problems, especially:
-
Abdominal or stomach bleeding or
-
Intestinal blockage - Cisapride may make these conditions worse
-
Heart disease or
-
Kidney disease, severe, or
-
Low potassium blood levels or
-
Lung disease, severe - Cisapride may cause an increased risk
of serious heart rhythm problems
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