Cisapride (Systemic)

Brand Names : Propulsid, Prepulsid

Proper Use of This Medicine

Take this medicine 15 minutes before meals and at bedtime with a beverage , unless otherwise directed by your doctor.

Grapefruit and grapefruit juice may increase the effects of cisapride by increasing the amount of this medicine in the body. You should not eat grapefruit or drink grapefruit juice while you are taking this medicine .

Dosing - The dose of cisapride will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of cisapride. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage forms (tablets and suspension):
  • For heartburn caused by gastroesophageal reflux:
    • Adults and children 12 years of age and older - 5 to 20 milligrams (mg) of cisapride two to four times a day. Cisapride should be taken fifteen minutes before meals and at bedtime.
    • Children up to 12 years of age - Dose is based on body weight and must be determined by your doctor. The dose is usually 0.15 to 0.3 mg of cisapride per kilogram (0.07 to 0.14 mg per pound) of body weight three to four times a day, fifteen minutes before meals.

Missed dose - If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage - To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.