Cough/Cold Combinations (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although serious side effects occur rarely when this medicine is taken as recommended, they may be more likely to occur if:

• too much medicine is taken.
• it is taken in large doses.
• it is taken for a long period of time.

Get emergency help immediately if any of the following symptoms of overdose occur :

For narcotic antitussive (codeine, dihydrocodeine, hydrocodone, or hydromorphone)-containing

Cold, clammy skin; confusion (severe); convulsions (seizures); drowsiness or dizziness (severe); nervousness or restlessness (severe); pinpoint pupils of eyes; slow heartbeat; slow or troubled breathing; weakness (severe)

For acetaminophen-containing

Diarrhea; increased sweating; loss of appetite; nausea or vomiting; stomach cramps or pain; swelling or tenderness in the upper abdomen or stomach area

For salicylate-containing

Any loss of hearing; bloody urine; confusion; convulsions (seizures); diarrhea (severe or continuing); dizziness or lightheadedness; drowsiness (severe); excitement or nervousness (severe); fast or deep breathing; fever; hallucinations (seeing, hearing, or feeling things that are not there); increased sweating; nausea or vomiting (severe or continuing); shortness of breath or troubled breathing (for salicylamide only); stomach pain (severe or continuing); uncontrollable flapping movements of the hands, especially in elderly patients; unusual thirst; vision problems

For decongestant-containing

Fast, pounding, or irregular heartbeat; headache (continuing and severe); nausea or vomiting (severe); nervousness or restlessness (severe); shortness of breath or troubled breathing (severe or continuing)

Also, check with your doctor as soon as possible if any of the following side effects occur:

For all combinations

Skin rash, hives, and/or itching

For antihistamine- or anticholinergic-containing

Clumsiness or unsteadiness; convulsions (seizures); drowsiness (severe); dryness of mouth, nose, or throat (severe); flushing or redness of face; hallucinations (seeing, hearing, or feeling things that are not there); restlessness (severe); shortness of breath or troubled breathing; slow or fast heartbeat

For iodine-containing

Headache (continuing); increased watering of mouth; loss of appetite; metallic taste; skin rash, hives, or redness; sore throat; swelling of face, lips, or eyelids

For acetaminophen-containing

Unexplained sore throat and fever; unusual tiredness or weakness; yellow eyes or skin

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

Constipation; decreased sweating; difficult or painful urination; dizziness or lightheadedness; drowsiness; dryness of mouth, nose, or throat; false sense of well-being; increased sensitivity of skin to sun; nausea or vomiting; nightmares; stomach pain; thickening of mucus; trouble in sleeping; unusual excitement, nervousness, restlessness, or irritability; unusual tiredness or weakness

Not all of the side effects listed above have been reported for each of these medicines, but they have been reported for at least one of them. There are some similarities among these combination medicines, so many of the above side effects may occur with any of these medicines.

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.