Dinoprostone (Cervical/Vaginal)
Brand Names : Cervidil, Prepidil, Prostin E, prostaglandin E 2, PGE 2
Proper Use of This MedicineAfter dinoprostone is given, you will need to lie down
for 10 minutes to 2 hours
so that the medicine can be absorbed. The
length of time you must remain lying down will depend on what form of the
medicine you are using.
Dosing - The dose of dinoprostone will be different
for different patients. The following information includes only the average
doses for dinoprostone. Your doctor will give you the dose of this medicine
and follow your care in a hospital or other health care setting.
-
For cervical
dosage form (gel):
-
To thin and widen the opening of the cervix just before labor:
-
Adults and teenagers - Your doctor will insert 0.5 milligram
(mg) (one application) of dinoprostone into the canal of your cervix. You
should remain lying on your back for at least ten to thirty minutes after
it has been applied.
-
For vaginal
dosage form (gel):
-
To cause the uterus to contract for labor:
-
Adults and teenagers - Your doctor will insert 1 milligram (mg)
(one applicatorful) of dinoprostone into your vagina. You should remain lying
on your back for at least thirty minutes after it has been applied. You may
need another dose of 1 to 2 mg six hours after the first dose.
-
For vaginal
dosage form (suppositories):
-
To cause the uterus to contract to abort a pregnancy:
-
Adults and teenagers - Your doctor will insert 20 milligrams
(mg) (one suppository) into your vagina every three to five hours as needed.
You should remain lying on your back for at least ten minutes after it has
been inserted.
-
For vaginal
dosage form (system):
-
To thin and widen the opening of the cervix just before labor:
-
Adults and teenagers - Your doctor will insert 10 milligrams
(mg) (one system) into your vagina. You should remain lying on your back for
at least two hours after it has been inserted.
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