Diuretics, Loop (Systemic)
Before Using This Medicine
In deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For loop diuretics,
the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to bumetanide, ethacrynic acid, furosemide, sulfonamides
(sulfa drugs), or thiazide diuretics (water pills). Also tell your health
care professional if you are allergic to any other substances, such as foods,
preservatives, or dyes.
Pregnancy - Studies have not been done in pregnant women. However,
studies in animals have shown this medicine to cause harmful effects.
In general, diuretics are not useful for normal swelling of feet and hands
that occurs during pregnancy. Diuretics should not be taken during pregnancy
unless recommended by your doctor.
Breast-feeding - These medicines have not been reported to cause
problems in nursing babies. Furosemide passes into breast milk; it is not
known whether bumetanide or ethacrynic acid passes into breast milk.
Children - Although there is no specific information comparing
the use of loop diuretics in children with use in any other age group, these
medicines are not expected to cause different side effects in children than
they do in adults.
Older adults - Dizziness, lightheadedness, or signs of too much
potassium loss may be more likely to occur in the elderly, who are more sensitive
to the effects of this medicine. Elderly patients may also be more likely
to develop blood clots.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
loop diuretics, it is especially important that your health care professional
know if you are taking any
Other medical problems - The presence of other medical
problems may affect the use of loop diuretics. Make sure you tell your doctor
if you have any other medical problems, especially:
Diabetes mellitus (sugar diabetes) - Loop diuretics may increase
the amount of sugar in the blood
Hearing problems or
Pancreatitis (inflammation of the pancreas) - Loop diuretics
may make these conditions worse
Heart attack, recent - Use of loop diuretics after a recent heart
attack may increase the chance of side effects
Kidney disease (severe) or
Liver disease - Higher blood levels of the loop diuretic may
occur, which may increase the chance of side effects
Lupus erythematosus (history of) - Ethacrynic acid and furosemide
may make this condition worse