Diuretics, Potassium-sparing, and Hydrochlorothiazide (Systemic)
Side Effects of This MedicineIn rats, spironolactone has been found to increase the risk of development
of tumors. However, the doses given were many times the dose of spironolactone
given to humans. It is not known whether spironolactone causes tumors in humans.
Along with its needed effects, a medicine may
cause some unwanted effects. Although not all of these side effects may occur,
if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side
effects occur:
Signs and symptoms of changes in potassium
Confusion; dryness of mouth; increased thirst; irregular heartbeat; mood or mental changes; muscle cramps or pain; numbness or tingling in hands,
feet, or lips; shortness of breath or difficulty
breathing; unusual tiredness or weakness; weak pulse; weakness or heaviness of
legs
Reported for triamterene only (rare)
Bright red tongue; burning, inflamed
feeling in tongue; cracked corners of mouth
Other side effects may occur that usually do not need medical attention.
These side effects may go away during treatment as your body adjusts to the
medicine. However, check with your doctor if any of the following side effects
continue or are bothersome:
More common (less common with triamterene)
Reported for spironolactone only (less common)
Breast tenderness in females; deepening
of voice in females; enlargement of breasts in males; increased hair growth in females; irregular menstrual periods; sweating
Spironolactone sometimes causes enlarged
breasts in males, especially when they take large doses of it for a long time.
Breasts usually decrease in size gradually over several months after this
medicine is stopped. If you have any questions about this, check with your
doctor.
Other side effects not listed above may also occur in
some patients. If you notice any other effects, check with your doctor.
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