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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Estrogens

Estrogens (Vaginal)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects

  • Urogenital symptoms suppressant - Conjugated Estrogens; Dienestrol; Estradiol; Estrone; Estropipate

Estrogens (ES-troe-jenz) are hormones produced by the body. Among other things, estrogens help develop and maintain female organs.

When your body is in short supply of this hormone, replacing it can ease uncomfortable changes that occur in the vagina, vulva (female genitals), and urethra (part of the urinary system). Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis).

Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens:

  • Dryness and soreness in the vagina
  • Itching, redness, or soreness of the vulva
  • Feeling an urge to urinate more often then is needed or experiencing pain while urinating
  • Pain during sexual intercourse

When used vaginally or on the skin, most estrogens are absorbed into the bloodstream and cause some, but not all, of the same effects as when they are taken by mouth. Estrogens used vaginally at very low doses for treating local problems of the genitals and urinary system will not protect against osteoporosis or stop the hot flushes caused by menopause.

Estrogens for vaginal use are available only with your doctor's prescription, in the following dosage forms:

  • Conjugated Estrogens
    • Cream (U.S. and Canada)
  • Dienestrol
    • Cream (U.S. and Canada)
  • Estradiol
    • Cream (U.S.)
    • Insert (or ring) (U.S. and Canada)
  • Estrone
    • Cream (Canada)
    • Suppositories (Canada)
  • Estropipate
    • Cream (U.S.)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Estrace 3
  • Estring 3
  • Ogen 5
  • Ortho Dienestrol 2
  • Premarin 1

In Canada -

  • Estring 3
  • Oestrilin 4
  • Ortho Dienestrol 2
  • Premarin 1

Other commonly used names are dienoestrol , oestradiol , and piperazine estrone sulfate .


For quick reference, the following estrogens are numbered to match the corresponding brand names.

This information applies to the following medicines
1. Conjugated Estrogens (CON-ju-gate-ed ES-troe-jenz)
2. Dienestrol (dye-en-ES-trole)
3. Estradiol (es-tra-DYE-ole)
4. Estrone (ES-trone)*
5. Estropipate (es-troe-PIH-pate)†
* Not commercially available in the U.S.
† Not commercially available in Canada


Next section


Estrogens: Before Using

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