Etretinate (Systemic)
Precautions While Using This MedicineYour doctor should check your progress at regular visits
to make sure this medicine does not cause unwanted effects.
Etretinate causes birth defects in humans if taken
during pregnancy. In addition, it is not known how long pregnancy should be
avoided after treatment stops, to prevent birth defects. Therefore, you must
plan on never having children if you are treated with etretinate. For as long
as you are able to become pregnant, you must use a reliable form of birth
control. In addition, you must not change your birth control method unless
you have checked with your doctor first. If you suspect that you may have
become pregnant while taking etretinate, stop taking the medicine immediately
and check with your doctor. Also, if you become pregnant at any time after
you have stopped taking this medicine, check with your doctor as soon as possible.
In either case, you should talk to your doctor about the risks of continuing
the pregnancy
.
It is not known how long etretinate stays in the blood. Therefore, to prevent the possibility of a pregnant patient receiving your
blood, you must plan on never donating blood to a blood bank if you are being
treated with etretinate or if you have ever been treated with etretinate
.
Do not take vitamin A or any vitamin supplement containing
vitamin A while you are taking this medicine
. To do so may increase
the chance of side effects.
Drinking too much alcohol while you are taking this medicine may cause
high triglyceride (fat-like substance) levels in the blood. This may increase
the chance of heart and blood vessel disease. Therefore, while taking this medicine, do not drink alcoholic beverages or, at least,
reduce the amount you usually drink
. If you have any questions about
this, check with your doctor.
For diabetic patients
:
-
This medicine may affect blood sugar levels. If you notice a change
in the results of your blood or urine sugar tests or if you have any questions,
check with your doctor.
In some patients, etretinate may cause a decrease in night vision. This
decrease may occur suddenly. If it does occur, do not
drive, use machines, or do anything else that could be dangerous if you are
not able to see well
. Also, check with your doctor.
Etretinate may cause dryness of the eyes. Therefore, if you wear contact
lenses, your eyes may be more sensitive to them while you are taking etretinate
and for several weeks or longer after you stop taking it. To help relieve
dryness of the eyes, check with your doctor about using an eye lubricating
solution, such as artificial tears. If your eyes become inflamed, check with
your doctor.
Some people who take this medicine may become more sensitive to sunlight
than they are normally. When you begin taking this medicine:
-
Stay out of direct sunlight, especially between the hours of 10:00
a.m. and 3:00 p.m., if possible.
-
Wear protective clothing, including a hat and sunglasses.
-
Apply a sun block product that has a skin protection factor (SPF)
of at least 15. Some patients may require a product with a higher SPF number,
especially if they have a fair complexion. If you have any questions about
this, check with your health care professional.
-
Do not use a sunlamp or tanning bed or booth.
If you have a severe reaction, check with your doctor
.
This medicine may cause dryness of the mouth and nose. For temporary relief
of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth,
or use a saliva substitute. However, if dry mouth continues for more than
2 weeks, check with your medical doctor or dentist. Continuing dryness of
the mouth may increase the chance of dental disease, including tooth decay,
gum disease, and fungus infections.
During the first month of treatment with etretinate, your psoriasis may
seem to get worse before it gets better. There may be more redness or itching,
but this usually goes away during treatment. It may take 2 or 3 months before
the full effects of etretinate are seen. If irritation or other symptoms of
your condition become severe, check with your doctor.
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