Factor VIIa (Systemic)
Brand Names : NovoSeven, coagulation factor VIIa (recombinant), eptacog alfa, factor 7, proconvertin, recombinant activated factor VIIa, recombinant coagulation factor VIIa, recombinant factor VIIa, rFVIIa.
Before Using This MedicineIn deciding to use a medicine,
the risks of using the medicine must be weighed against the good it will do.
This is a decision you and your doctor will make. For factor VIIa, the following
should be considered:
Allergies - Tell your doctor if you have ever had any unusual
or allergic reaction to factor VIIa or to any products that contain mouse,
hamster, or cow proteins. Also tell your doctor and pharmacist if you are
allergic to any other substances, such as foods, preservatives, or dyes.
Pregnancy - Studies on effects in pregnancy have not been done
in humans.
Breast-feeding - It is not known whether factor VIIa passes into
breast milk. However, because this medicine may cause serious side effects,
breast-feeding is generally not recommended while you are receiving it.
Children - This medicine has been tested in children and no
side effects or problems were found that were different from those seen in
adults.
Older adults - No information is available about the use of factor
VIIa in older adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
factor VIIa, it is especially important that your doctor and pharmacist know
if you are taking any of the following:
-
Activated prothrombin complex concentrates (ie, FEIBA, Autoplex T)
or
-
Prothrombin complex concentrates (ie, AlphaNine, BeneFix) - May
increase the risk of side effects
Other medical problems - The presence of medical problems
may affect the use of factor VIIa. Make sure to tell your doctor if you have
any medical problems, especially:
-
Blood clots or a history of medical problems caused by blood clots
or
-
Heart disease or
-
Infection or
-
Injury (crush) - These conditions may increase the risk of bleeding
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