Fluoroquinolones (Systemic)

Side Effects of This Medicine

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common - For sparfloxacin and moxifloxacin (less common)

Fainting; irregular or slow heart rate

Less common - More common for lomefloxacin and sparfloxacin

bloating or swelling of face, arms, hands, lower legs, or feet; blistering of skin; blurred vision; dizziness; headache; nervousness; pounding in the ears; rapid weight gain; sensation of skin burning; slow or fast heartbeat; skin itching, rash, redness, or swelling; tingling of hands or feet; unusual weight gain or loss

Rare

Abdominal or stomach cramps and pain (severe); abdominal pain; abdominal tenderness; agitation; area rash; black, tarry stools; bleeding; blisters on mucous membranes, with fever; blistering, itching, loosening, peeling, or redness of skin; bloody or cloudy urine; coldness; burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings; chills; chest pain; clay-colored stools; confusion; cough; dark or amber urine; diarrhea (watery and severe, which may also be bloody); difficulty breathing; difficulty swallowing; discoloration of skin; dizziness; dry mouth; excessive muscle tone; fainting; faintness, dizziness, or lightheadedness when getting up from a lying or sitting position suddenly; fast, pounding, or irregular heartbeat or pulse; fatigue; flushed, dry skin; feeling of pressure; feeling of unreality; feeling of warmth or heat; fever; flushing or redness of skin especially on face and neck; fruit-like breath odor; hallucinations (seeing, hearing, or feeling things that are not there); hives or welts; incoordination; increased hunger; increased thirst; increased urination; inflammation; infection; irregular or fast heart rate; itching; joint pain; lack or loss of strength; large amount of fat in the blood; loss of appetite; loss of memory; lower back, side, or stomach pain; lumps; muscle stiffness; muscle tension or tightness; nausea; noisy breathing; numbness; pain; pain at site of injection - for ciprofloxacin or ofloxacin injection; pain in calves, radiating to heels; pain, warmth, or burning in fingers, toes and legs; painful or difficult urination; pale stools; palpitations; peeling of the skin; problems with memory; problems with speech or speaking; problems with vision or hearing; rash; rash with flat lesions or small raised lesions on the skin; redness; redness of skin; redness, swelling, or soreness of tongue; scarring; seizures; sense of detachment from self or body; shakiness or tremors; shortness of breath skin rash; sore throat; sores, ulcers, or white spots on lips or in mouth; soreness; stomach pain; stinging; sweating; swelling; swelling of face or neck; swelling of calves, feet, or lower legs; swelling or inflammation of the mouth; swelling or puffiness of face; tenderness; tightness in chest; tingling; troubled breathing; ulceration; unpleasant breath odor; unusual tiredness or weakness; vomiting; vomiting of blood; warmth; wheezing; yellow eyes or skin

Incidence not determined - �Observed during clinical practice with levofloxacin; estimates of frequency cannot be determined

abnormal brain wave patterns; black, tarry stools; bleeding gums; blurred vision; coma; confusion; difficult breathing; failure of the heart, lungs, kidneys and/or liver; fatigue; general body swelling; hives; increased bleeding time; irregular reading on a electrocardiogram (heart test); joint or muscle pain; sharp drop in blood pressure; sore throat; swollen glands; unusual bleeding or bruising

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:

More common

Abdominal or stomach pain or discomfort (mild); diarrhea (mild); drowsiness; lightheadedness; nervousness; trouble in sleeping; vaginal pain and discharge

Less frequent or rare

Abnormal dream; acid or sour stomach; back pain; bad, unusual or unpleasant (after) taste; belching; bloated full feeling; burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings; burning feeling in chest or stomach; change in sense of taste; change in sense of smell; change in taste; change in vision; constipation; continuing ringing or buzzing or other unexplained noise in ears; crying; depersonalization; depression; difficulty in moving; difficulty in sleeping; difficulty in speaking; difficulty in urination; dysphoria; euphoria; excess air or gas in stomach or intestines; fear; feeling of constant movement of self or surroundings; general feeling of discomfort or illness; hearing loss; heartburn; impaired vision; increased sensitivity of skin to sunlight; indigestion; mental depression; muscle pain; pain, swelling, or redness in joints; paranoia; passing gas; pelvic pain; pinpoint red or purple spots on skin; puffiness or swelling of the eyelids or around the eyes, face, lips or tongue; quick to react or overreact emotionally; rapidly changing moods; sensation of spinning; shortness of breath; sleeplessness; sleepiness or unusual drowsiness; sore mouth or tongue, or white patches in mouth and/or on tongue; spots on skin resembling a blister or pimple; stomach discomfort, upset or pain; tenderness in stomach area; thinking, abnormal; tongue discoloration; unable to sleep; vaginal yeast infection; vision problems; weight loss

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.