Gold Compounds (Systemic)
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For gold compounds,
the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to gold or other metals, if you have received a gold compound
before and developed serious side effects from it, or if any medicine you
have taken has caused an allergy or a reaction that affected your blood. Also
tell your health care professional if you are allergic to any other substances,
such as foods, preservatives, or dyes.
Pregnancy - Studies on birth defects with gold compounds have
not been done in humans. However, studies in animals have shown that gold
compounds may cause birth defects.
Breast-feeding - Aurothioglucose and gold sodium thiomalate pass
into the breast milk and may cause unwanted effects in nursing babies. It
is not known whether auranofin passes into the breast milk.
Children - Auranofin has been tested only in adult patients
and there is no specific information about its use in children. However, aurothioglucose
and gold sodium thiomalate have been tested in children and have not been
shown to cause different side effects or problems than they do in adults.
Older adults - These medicines have been tested and have not been
shown to cause different side effects or problems in older people than they
do in younger adults.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
a gold compound, it is important that your health care professional know if
you are taking any
other prescription or nonprescription
(over-the-counter [OTC]) medicine, especially:
-
Penicillamine (e.g., Cuprimine) - The chance of side effects
may be increased.
Other medical problems - The presence of other medical
problems may affect the use of gold compounds. Make sure you tell your doctor
if you have any other medical problems, especially:
-
Blood or blood vessel disease or
-
Colitis or
-
Kidney disease (or history of) or
-
Lupus erythematosus or
-
Sj�gren's syndrome or
-
Skin disease - The chance of unwanted effects may be increased
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