Heparin (Systemic)
Brand Names : Calciparine, Liquaemin, Calcilean, Hepalean, Heparin Leo
Before Using This MedicineIn deciding to use a medicine,
the risks of taking the medicine must be weighed against the good it will
do. This is a decision you and your doctor will make. For heparin, the following
should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to heparin, to beef, or to pork. Also tell your health care
professional if you are allergic to any other substances, such as foods, preservatives,
or dyes.
Pregnancy - Heparin has not been shown to cause birth defects
or bleeding problems in the baby. However, use during the last 3 months of
pregnancy or during the month following the baby's delivery may cause bleeding
problems in the mother.
Breast-feeding - Heparin does not pass into the breast milk. However,
heparin can rarely cause bone problems in the nursing mother. This effect
has been reported to occur when heparin is used for 2 weeks or more. Be sure
to discuss this with your doctor.
Children - Heparin has been tested in children and, in effective
doses, has not been shown to cause different side effects or problems than
it does in adults.
Older adults - Bleeding problems may be more likely to occur in
elderly patients, especially women, who are usually more sensitive than younger
adults to the effects of heparin.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. When you are taking
heparin, it is especially important that your health care professional know
if you are taking any of the following:
-
Aspirin or
-
Carbenicillin by injection (e.g., Geopen) or
-
Cefamandole (e.g., Mandol) or
-
Cefoperazone (e.g., Cefobid) or
-
Cefotetan (e.g., Cefotan) or
-
Dipyridamole (e.g., Persantine) or
-
Divalproex (e.g., Depakote) or
-
Medicine for inflammation or pain, except narcotics, or
-
Medicine for overactive thyroid or
-
Pentoxifylline (e.g., Trental) or
-
Plicamycin (e.g., Mithracin) or
-
Probenecid (e.g., Benemid) or
-
Sulfinpyrazone (e.g., Anturane) or
-
Ticarcillin (e.g., Ticar) or
-
Valproic acid (e.g., Depakene) - Using any of these medicines
together with heparin may increase the risk of bleeding
-
Also, tell your doctor if you are now receiving any kind of medicine
by intramuscular (IM) injection.
Other medical problems - The presence of other medical
problems may affect the use of heparin. Make sure you tell your doctor if
you have any other medical problems, especially:
-
Allergies or asthma (history of) - The risk of an allergic reaction
to heparin may be increased
-
Blood disease or bleeding problems or
-
Colitis or stomach ulcer (or history of) or
-
Diabetes mellitus (sugar diabetes) (severe) or
-
High blood pressure (hypertension) or
-
Kidney disease or
-
Liver disease or
-
Tuberculosis (active) - The risk of bleeding may be increased
Also, tell your doctor if you have received heparin before and had a reaction
to it called thrombocytopenia, or if new blood clots formed while you were
receiving the medicine.
In addition, it is important that you tell your doctor if you have recently
had any of the following conditions or medical procedures:
-
Childbirth or
-
Falls or blows to the body or head or
-
Heavy or unusual menstrual bleeding or
-
Insertion of intrauterine device (IUD) or
-
Medical or dental surgery or
-
Spinal anesthesia or
-
X-ray (radiation) treatment - The risk of serious bleeding may
be increased
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