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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Histamine H 2-receptor Antagonists

Histamine H 2-receptor Antagonists (Systemic)

Description and Brand Names | Before Using | Proper Use | Precautions | Side Effects | Additional Information

Category
  • Histamine H 2 -receptor antagonist - Cimetidine; Famotidine; Nizatidine; Ranitidine
  • Antiulcer agent - Cimetidine; Famotidine; Nizatidine; Ranitidine
  • Gastric acid secretion inhibitor - Cimetidine; Famotidine; Nizatidine; Ranitidine
  • Urticaria therapy adjunct - Cimetidine
Description

Histamine H 2 -receptor antagonists, also known as H 2 -blockers, are used to treat duodenal ulcers and prevent their return. They are also used to treat gastric ulcers and for some conditions, such as Zollinger-Ellison disease, in which the stomach produces too much acid. In over-the-counter (OTC) strengths, these medicines are used to relieve and/or prevent heartburn, acid indigestion, and sour stomach. H 2 -blockers may also be used for other conditions as determined by your doctor.

H 2 -blockers work by decreasing the amount of acid produced by the stomach.

They are available in the following dosage forms:

    Oral
  • Cimetidine
    • Oral solution (U.S. and Canada)
    • Tablets (U.S. and Canada)
  • Famotidine
    • Oral suspension (U.S.)
    • Tablets (U.S. and Canada)
    • Chewable tablets (U.S. and Canada)
    • Oral disintegrating tablets (U.S.)
  • Nizatidine
    • Capsules (U.S. and Canada)
    • Tablets (U.S.)
  • Ranitidine
    • Effervescent granules (U.S.)
    • Syrup (U.S. and Canada)
    • Tablets (U.S. and Canada)
    • Effervescent tablets (U.S.)
    Parenteral
  • Cimetidine
    • Injection (U.S. and Canada)
  • Famotidine
    • Injection (U.S. and Canada)
  • Ranitidine
    • Injection (U.S. and Canada)

Brand Names

Some commonly used brand names are:

In the U.S. -

  • Axid 3
  • Axid AR 3
  • Mylanta AR Acid Reducer 2
  • Pepcid 2
  • Pepcid I.V. 2
  • Pepcid AC Acid Controller 2
  • Pepcid RPD 2
  • Tagamet 1
  • Tagamet HB 1
  • Zantac 4
  • Zantac EFFERdose Granules 4
  • Zantac EFFERdose Tablets 4

In Canada -

  • Acid Control 2
  • Act 2
  • Apo-Cimetidine 1
  • Apo-Famotidine 2
  • Apo-Nizatidine 3
  • Apo-Ranitidine 4
  • Axid 3
  • Dyspep HB 2
  • Gen-Cimetidine 1
  • Gen-Famotidine 2
  • Gen-Ranitidine 4
  • Maalox H2 Acid Controller 2
  • Novo-Cimetine 1
  • Novo-Famotidine 2
  • Novo-Ranitidine 4
  • Nu-Cimet 1
  • Nu-Famotidine 2
  • Nu-Ranit 4
  • Pepcid 2
  • Pepcid AC 2
  • Pepcid I.V. 2
  • Peptol 1
  • PMS-Cimetidine 1
  • Tagamet 1
  • Ulcidine 2
  • Ulcidine-HB 2
  • Zantac 4
  • Zantac 75 4

Note:

For quick reference, the following histamine H 2-receptor antagonists are numbered to match the corresponding brand names.

This information applies to the following medicines:
1. Cimetidine (sye-MET-i-deen)‡§
2. Famotidine (fa-MOE-ti-deen)§
3. Nizatidine (ni-ZA-ti-deen)
4. Ranitidine (ra-NIT-ti-deen)‡
‡ Generic name product may be available in the U.S.
§ Generic name product may be available in Canada

   

Next section

   

Histamine H 2-receptor Antagonists: Before Using



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