Isoniazid (Systemic)
Brand Names : Laniazid, Nydrazid, Isotamine, PMS Isoniazid, INH
Proper Use of This MedicineIf you are
taking isoniazid by mouth and it upsets your stomach, take it with food. Antacids
may also help. However, do not take aluminum-containing antacids within 1
hour of taking isoniazid. They may keep this medicine from working properly.
For patients taking the oral liquid form
of
isoniazid:
-
Use a specially marked measuring spoon or other device to measure
each dose accurately. The average household teaspoon may not hold the right
amount of liquid.
To help clear up your tuberculosis (TB) completely, it is very important that you keep taking this medicine for the full time
of treatment
, even if you begin to feel better after a few weeks. You
may have to take it every day for as long as 6 months to 2 years. It is important that you do not miss any doses
.
Your doctor may also want you to take pyridoxine (e.g., Hexa-Betalin, vitamin
B 6
) every day to help prevent or lessen some
of the side effects of isoniazid. This is not usually needed in children,
who receive enough pyridoxine in their diet. If it is needed, it is very important to take pyridoxine every day along with this medicine.
Do not miss any doses
.
Dosing - The dose of isoniazid will be different for
different patients. Follow your doctor's orders or the
directions on the label
. The following information includes only the
average doses of isoniazid. If your dose is different,
do not change it
unless your doctor tells you to do so. The number of tablets or teaspoonfuls of syrup that you take depends on
the strength of the medicine.
-
For oral
dosage forms (tablets, syrup):
-
For preventing the return (reactivation) of tuberculosis:
-
Adults and teenagers - 300 milligrams (mg) once a day.
-
Children - Dose is based on body weight. The usual dose is 10
mg per kilogram (kg) (4.5 mg per pound) of body weight, up to 300 mg, once
a day.
-
For treatment of tuberculosis:
-
Adults and teenagers - 300 mg once a day; or 15 mg per kg (6.8
mg per pound) of body weight, up to 900 mg, two times a week or three times
a week, depending on the schedule your doctor chooses for you.
-
Children - Dose is based on body weight. The usual dose is 10
to 20 mg per kg (4.5 to 9.1 mg per pound) of body weight, up to 300 mg, once
a day; or 20 to 40 mg per kg (9.1 to 18.2 mg per pound) of body weight, up
to 900 mg, two times a week or three times a week, depending on the schedule
your doctor chooses for you.
-
For injection
dosage form:
-
For preventing the return (reactivation) of tuberculosis:
-
Adults and teenagers - 300 mg once a day.
-
Children - Dose is based on body weight. The usual dose is 10
mg per kg (4.5 mg per pound) of body weight, up to 300 mg, once a day.
-
For treatment of tuberculosis:
-
Adults and teenagers - 300 mg once a day; or 15 mg per kg (6.8
mg per pound) of body weight, up to 900 mg, two times a week or three times
a week, depending on the schedule your doctor chooses for you.
-
Children - Dose is based on body weight. The usual dose is 10
to 20 mg per kg (4.5 to 9.1 mg per pound) of body weight, up to 300 mg, once
a day; or 20 to 40 mg per kg (9.1 to 18.2 mg per pound) of body weight, up
to 900 mg, two times a week or three times a week, depending on the schedule
your doctor chooses for you.
Missed dose - If you miss a dose of this medicine, take it as
soon as possible. However, if it is almost time for your next dose, skip the
missed dose and go back to your regular dosing schedule. Do not double doses.
Storage - To store this medicine:
-
Keep out of the reach of children.
-
Store away from heat and direct light.
-
Do not store the tablet form of this medicine in the bathroom, near
the kitchen sink, or in other damp places. Heat or moisture may cause the
medicine to break down.
-
Keep the oral liquid form of this medicine from freezing.
-
Do not keep outdated medicine or medicine no longer needed. Be sure
that any discarded medicine is out of the reach of children.
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