Ketoconazole (Topical)
Brand Names : Nizoral Cream, Nizoral A-D Shampoo, Nizoral Shampoo
Before Using This MedicineIn deciding to use a medicine,
the risks of using the medicine must be weighed against the good it will do.
This is a decision you and your doctor will make. For topical ketoconazole,
the following should be considered:
Allergies - Tell your doctor if you have ever had any unusual or
allergic reaction to ketoconazole, miconazole or other imidazoles, or sulfites.
The cream form of ketoconazole contains sulfites. Also tell your health care
professional if you are allergic to any other substances, such as preservatives
or dyes.
Pregnancy - Ketoconazole has not been studied in pregnant women.
However, studies in animals have shown that ketoconazole causes birth defects
or other problems. Before using this medicine, make sure your doctor knows
if you are pregnant or if you may become pregnant.
Breast-feeding - It is not known whether topical ketoconazole, used
on a regular basis, is absorbed into the mother's body enough to pass into
the breast milk. However, the cream was not absorbed through the skin after
a single dose was applied to the chest, back, and arms of volunteers. Also,
the shampoo was not absorbed through the skin after frequent shampooing by
volunteers. Therefore, it is unlikely to cause problems in nursing babies.
Children - Studies on this medicine have been done only in adult
patients, and there is no specific information comparing use of this medicine
in children with use in other age groups.
Older adults - Many medicines have not been studied specifically
in older people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different side effects
or problems in older people. There is no specific information comparing use
of topical ketoconazole in the elderly with use in other age groups.
Other medicines - Although certain medicines should not be used
together at all, in other cases two different medicines may be used together
even if an interaction might occur. In these cases, your doctor may want to
change the dose, or other precautions may be necessary. Tell your health care
professional if you are using any other prescription or nonprescription (over-the-counter
[OTC]) medicine.
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