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You are here : 3-RX.com > Drugs & Medications > Detailed Drug Information (USP DI) > Maprotiline : Before Using

Maprotiline (Systemic)

Brand Names : Ludiomil

Maprotiline | Before Using | Proper Use | Precautions | Side Effects | Additional Information

Before Using This Medicine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For maprotiline, the following should be considered:

Allergies - Tell your doctor if you have ever had any unusual or allergic reaction to maprotiline or tricyclic antidepressants. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy - Maprotiline has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies.

Breast-feeding - Maprotiline passes into the breast milk. However, this medicine has not been reported to cause problems in nursing babies.

Children - Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of maprotiline in children with use in other age groups.

Older adults - Drowsiness, dizziness or lightheadedness; confusion; vision problems; dryness of mouth; constipation; and difficulty in urinating may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to the effects of maprotiline.

Other medicines - Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking maprotiline, it is especially important that your health care professional know if you are taking any of the following:

  • Amphetamines or
  • Appetite suppressants (diet pills) or
  • Medicine for asthma or other breathing problems or
  • Medicine for colds, sinus problems, or hay fever or other allergies (including nose drops or sprays) - Using these medicines with maprotiline may cause serious unwanted effects on your heart and blood pressure
  • Central nervous system (CNS) depressants (medicines that cause drowsiness) - Taking these medicines with maprotiline may increase the CNS depressant effects
  • Monoamine oxidase (MAO) inhibitor activity (isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], tranylcypromine [e.g., Parnate]) - Taking maprotiline while you are taking or within 2 weeks of taking monoamine oxidase (MAO) inhibitors may cause very serious side effects, such as sudden high body temperature, extremely high blood pressure, and severe convulsions; at least 14 days should be allowed between stopping treatment with one medicine and starting treatment with the other

Other medical problems - The presence of other medical problems may affect the use of maprotiline. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alcohol abuse or
  • Seizure disorders (including epilepsy) - The risk of seizures may be increased
  • Asthma or
  • Difficult urination or
  • Enlarged prostate or
  • Glaucoma or
  • Mental illness (severe) or
  • Stomach or intestinal problems - Maprotiline may make the condition worse
  • Heart or blood vessel disease or
  • Overactive thyroid - Serious effects on your heart may occur
  • Liver disease - Higher blood levels of maprotiline may occur, increasing the chance of side effects

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Maprotiline: Description and Brand Names

 

Maprotiline: Proper Use



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